SCHEMBL2983076

SCHEMBL2983076

O=C(O)c1cccc(=O)n1OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.49
TSHR P16473 2/20 0.49
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
ALOX15 P16050 1/20 0.42
NR4A2 P43354 2/20 0.40
IDH1 O75874 2/20 0.39
NR4A1 P22736 1/20 0.39
NR4A3 Q92570 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HBB P68871 1/20 0.39
KMT2A Q03164 2/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21404871 0.98 ALDH1A1 (0.48) ALDH1A1TSHRKEAP1NFE2L2ALOX15
SCHEMBL13531464 0.88 ALDH1A1 (0.47) ALDH1A1TSHRKEAP1NFE2L2ALOX15
SCHEMBL13531457 0.88 ALDH1A1 (0.50) ALDH1A1TSHRKEAP1NFE2L2ALOX15
SCHEMBL29604362 0.88 ALDH1A1 (0.47) ALDH1A1TSHRKEAP1NFE2L2ALOX15
SCHEMBL29946854 0.85 ALDH1A1 (0.48) ALDH1A1TSHRKEAP1NFE2L2ALOX15
SCHEMBL29793790 0.83 KEAP1 (0.48) ALDH1A1TSHRKEAP1NFE2L2ALOX15
SCHEMBL38652019 0.83 KEAP1 (0.48) ALDH1A1TSHRKEAP1NFE2L2KMT2A
SCHEMBL29793704 0.83 KEAP1 (0.48) ALDH1A1TSHRKEAP1NFE2L2KDM4E
SCHEMBL38651961 0.83 KEAP1 (0.64) ALDH1A1TSHRKEAP1NFE2L2KMT2A
SCHEMBL38652308 0.81 RAB9A (0.53) KEAP1NFE2L2L3MBTL1HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116803985-A Rare earth fluorescent complex, time-resolved fluorescent microsphere, and preparation methods and applications thereof 广州万孚生物技术股份有限公司 2023-09-26 CN claimed
US-12479792-B2 Compositions of chelating molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-11-25 US disclosed
US-12440584-B2 Macrocyclic ligands with pendant chelating moieties and complexes thereof LUMIPHORE, INC. (US) 2025-10-14 US disclosed
US-20250090696-A1 MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF LUMIPHORE, INC. 2025-03-20 US disclosed
US-20240304351-A1 SEPARATION OF METAL IONS BY LIQUID-LIQUID EXTRACTION UNIV CALIFORNIA (US) 2024-09-12 US disclosed
US-12002595-B2 Separation of metal ions by liquid-liquid extraction THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-04 US disclosed
US-20240139333-A1 2,6-DICHLOROPHENYL ESTER COMPOUNDS AND USE THEREOF FUSION PHARMACEUTICALS INC (CA) 2024-05-02 US disclosed
EP-4346787-A1 2,6-DICHLOROPHENYL ESTER COMPOUNDS AND USE THEREOF Fusion Pharmaceuticals Inc. (CA) 2024-04-10 EP disclosed
US-11951188-B2 Macrocyclic ligands with pendant chelating moieties and complexes thereof LUMIPHORE, INC. (US) 2024-04-09 US disclosed
US-20240067650-A1 MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF LUMIPHORE, INC. 2024-02-29 US disclosed
EP-2044090-A2 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-08 EP disclosed
EP-1423399-A4 HYDROXYPYRIDONATE AND HYDROXYPYRIMIDINONE CHELATING AGENTS UNIV CALIFORNIA (US) 2008-05-07 EP disclosed
WO-2008008797-A2 LUMINESCENT 1-HYDROXY-2-PYRIDINONE CHELATES OF LANTHANIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-01-17 WO disclosed
WO-2007121453-A2 2-HYDROXY-1-OXO 1,2 DIHYDRO ISOQUINOLINE CHELATING AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-10-25 WO disclosed
US-20070117848-A1 METALLOPROTEIN INHIBITORS REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO 2007-05-24 US disclosed
US-6846915-B2 Hydroxypyridonate and hydroxypyrimidinone chelating agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-01-25 US disclosed
US-20050008570-A1 Hydroxypyridonate and hydroxypyrimidinone chelating agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-01-13 US disclosed
EP-1423399-A2 HYDROXYPYRIDONATE AND HYDROXYPYRIMIDINONE CHELATING AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-06-02 EP disclosed
US-20030095922-A1 Hydroxypyridonate and hydroxypyrimidinone chelating agents REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-05-22 US disclosed
WO-2003016923-A2 HYDROXYPYRIDONATE AND HYDROXYPYRIMIDINONE CHELATING AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050008570-A1 Hydroxypyridonate and hydroxypyrimidinone chelating agents HAMP, GDI1, MPI ALDH1A1 2521/4885TSHR 3682/4885KEAP1 501/4885
US-20240067650-A1 MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF TFRC, CLTC, SLC39A3 ALDH1A1 2862/4885TSHR 477/4885KEAP1 2708/4885
US-12440584-B2 Macrocyclic ligands with pendant chelating moieties and complexes thereof TFRC, CLTC, SLC39A3 ALDH1A1 2862/4885TSHR 477/4885KEAP1 2708/4885
US-12002595-B2 Separation of metal ions by liquid-liquid extraction SLC39A14, SLC39A11, SLC39A7 ALDH1A1 4783/4885TSHR 1492/4885KEAP1 4087/4885
US-20250090696-A1 MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF TFRC, CLTC, SLC39A3 ALDH1A1 2862/4885TSHR 477/4885KEAP1 2708/4885
US-20240139333-A1 2,6-DICHLOROPHENYL ESTER COMPOUNDS AND USE THEREOF DDT, GSTA2, CYP2D6 ALDH1A1 152/4885TSHR 2077/4885KEAP1 360/4885
US-12479792-B2 Compositions of chelating molecules CACYBP, FTH1, TFRC ALDH1A1 4177/4885TSHR 3275/4885KEAP1 2316/4885
US-20070117848-A1 METALLOPROTEIN INHIBITORS SOD1, ZFX, SOD3 ALDH1A1 918/4885TSHR 1588/4885KEAP1 384/4885
US-11951188-B2 Macrocyclic ligands with pendant chelating moieties and complexes thereof TFRC, CLTC, SLC39A3 ALDH1A1 2862/4885TSHR 477/4885KEAP1 2708/4885
US-20240304351-A1 SEPARATION OF METAL IONS BY LIQUID-LIQUID EXTRACTION SLC39A14, SLC39A11, SLC39A7 ALDH1A1 4783/4885TSHR 1492/4885KEAP1 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.