Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23648221 | 0.92 | LMNA (0.32) | LMNA | |
| Potassium Ion SCHEMBL23835503 | 0.88 | LMNA (0.30) | LMNA | |
| SCHEMBL23648013 | 0.80 | LMNA (0.30) | LMNA | |
| Potassium Ion SCHEMBL10969351 | 0.75 | LMNA (0.32) | LMNA | |
| Potassium Ion SCHEMBL23835549 | 0.73 | — | — | |
| Potassium Ion SCHEMBL8010764 | 0.72 | LMNA (0.37) | LMNA | |
| SCHEMBL999875 | 0.67 | LMNA (0.32) | LMNA | |
| Lithium Ion SCHEMBL11661857 | 0.67 | LMNA (0.32) | LMNA | |
| Perflutren SCHEMBL1446805 | 0.66 | LMNA (0.43) | LMNA | |
| Perflubutane SCHEMBL9051673 | 0.66 | LMNA (0.54) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357172-A1 | Perfluorinated Allyl Ethers and Perfluorinated Allyl Amines and Methods of Making and Using the Same | 3M INNOVATIVE PROPERTIES COMPANY | 2023-11-09 | — | — | US | disclosed |
| EP-4121405-A1 | PERFLUORINATED ALLYL ETHERS AND PERFLUORINATED ALLYL AMINES AND METHODS OF MAKING AND USING THE SAME | 3M Innovative Properties Company (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021186271-A1 | PERFLUORINATED ALLYL ETHERS AND PERFLUORINATED ALLYL AMINES AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357172-A1 | Perfluorinated Allyl Ethers and Perfluorinated Allyl Amines and Methods of Making and Using the Same | AFF1, AFF2, AFF4 | LMNA 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.