SCHEMBL999875

SCHEMBL999875

[Na+].[O-]C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.32

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL10969351 0.92 LMNA (0.32) LMNA
Lithium Ion SCHEMBL11661857 0.92 LMNA (0.32) LMNA
SCHEMBL28889669 0.85 LMNA (0.42) LMNA
Tetramethylammonium Ion SCHEMBL15873984 0.82
SCHEMBL15874025 0.82
Potassium Ion SCHEMBL8010764 0.80 LMNA (0.37) LMNA
SCHEMBL38655461 0.77
Tetramethylammonium Ion SCHEMBL21062100 0.72 LMNA (0.32) LMNA
Tetramethylammonium Ion SCHEMBL23909443 0.70 LMNA (0.36) LMNA
Tetramethylammonium Ion SCHEMBL23909442 0.70 LMNA (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1788655-B1 Polymer membrane for fuel cell, method of preparing same, and membrane-electrode assemby for fuel cell comprising same SAMSUNG SDI CO LTD (KR) 2015-09-09 EP disclosed
US-7871736-B2 Polymer membrane for fuel cell, method of preparing same, and membrane-electrode assembly for fuel cell comprising same SAMSUNG SDI CO., LTD. (KR) 2011-01-18 US disclosed
US-20070117000-A1 polyelectrolyte is a polyphenylene ether, a polyphenylene thioether, a copolymer of polyether ketone polymer, or polyether sulfone polymer; having a fluoroalkyl group and a proton conductive group; electroconductive polymers SAMSUNG SDI CO., LTD., A CORPORATION ORGANIZED UNDER THE LAWS OF THE REPUBLIC OF KOREA (KR) 2007-05-24 US disclosed
EP-1788655-A1 Polymer membrane for fuel cell, method of preparing same, and membrane-electrode assemby for fuel cell comprising same Samsung SDI Co., Ltd. (KR) 2007-05-23 EP disclosed
US-4093775-A TREATMENT WITH CONDENSATION PRODUCTS OF 6-HYDROXYHEXYL PERFLUOROISOPROPYL ETHER AND ETHYLENE OXIDE AND 2,2,3,4,4,4-HEXAFLUOROBUTANOL AND PROPYLENE OXIDE, ANTISTATIC AGENTS DIAMOND SHAMROCK CORPORATION (US) 1978-06-06 US disclosed
US-3980715-A ETHOXYLATES OF 6-HYDROXYHEXYL PERFLUOROISOPROPYL ETHER; ANTISTATIC AGENTS AND LUBRICANTS DIAMOND SHAMROCK CORPORATION (US) 1976-09-14 US disclosed