Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889669 | 0.89 | LMNA (0.42) | LMNACA1CA2MMP1MMP2 | |
| Potassium Ion SCHEMBL10969351 | 0.88 | LMNA (0.32) | LMNA | |
| Tetramethylammonium Ion SCHEMBL21062100 | 0.83 | LMNA (0.32) | LMNA | |
| Tetramethylammonium Ion SCHEMBL23909442 | 0.81 | LMNA (0.36) | LMNACA1CA2MMP1MMP2 | |
| Tetramethylammonium Ion SCHEMBL23909443 | 0.81 | LMNA (0.36) | LMNACA1CA2MMP1MMP2 | |
| Lithium Ion SCHEMBL11661857 | 0.80 | LMNA (0.32) | LMNA | |
| SCHEMBL999875 | 0.80 | LMNA (0.32) | LMNA | |
| Potassium Ion SCHEMBL28596070 | 0.74 | LMNA (0.35) | LMNACA1CA2MMP1MMP2 | |
| Perflubutane SCHEMBL111514 | 0.73 | LMNA (0.54) | LMNACA1CA2MMP1MMP2 | |
| Perflubutane SCHEMBL9051673 | 0.73 | LMNA (0.54) | LMNACA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051381-A1 | PROCESS FOR PREPARING HYDROFLUOROETHERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-11-15 | — | — | EP | disclosed |
| US-6023002-A | REACTION OF A FLUORINATED ALKOXIDE WITH AN ALKYL FLUOROVINYLALKYL ETHER, THE ALKYL FLUOROVINYLALKYL ETHER HAVING ALPHA-BETA CARBON-CARBON UNSATURATION RELATIVE TO THE ETHER OXYGEN | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-02-08 | — | — | US | disclosed |
| WO-1999037598-A1 | PROCESS FOR PREPARING HYDROFLUOROETHERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-07-29 | — | — | WO | disclosed |