Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25767922 | 0.81 | MEN1 (0.42) | ALDH1A1KDM4ECXCR2MEN1KMT2A | |
| SCHEMBL25767923 | 0.76 | PRKCZ (0.39) | ALDH1A1KDM4EHTTTAS1R3TAS1R1 | |
| SCHEMBL25802048 | 0.72 | ALDH1A1 (0.42) | ALDH1A1PKMKDM4EHTTPTK2 | |
| SCHEMBL22800128 | 0.71 | GABRA1 (0.44) | — | |
| SCHEMBL20094597 | 0.71 | MAPT (0.45) | ALDH1A1HTTTAS1R3TAS1R1MEN1 | |
| SCHEMBL9645439 | 0.69 | SIRT1 (0.40) | KDM4E | |
| SCHEMBL2577569 | 0.69 | KDM4E (0.41) | ALDH1A1PKMKDM4EHTTMEN1 | |
| SCHEMBL12260795 | 0.68 | MMP2 (0.55) | ALDH1A1PKMKDM4EHTTCXCR2 | |
| SCHEMBL13180284 | 0.67 | MEN1 (0.53) | ALDH1A1PKMKDM4EHTTADRA1D | |
| SCHEMBL18893268 | 0.67 | ALDH1A1 (0.59) | ALDH1A1PKMKDM4EHTTADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11124497-B1 | Inhibitors of cysteine proteases and methods of use thereof | Pardes Biosciences, Inc. (US) | 2021-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124497-B1 | Inhibitors of cysteine proteases and methods of use thereof | CTRL, CTSV, CTSL | ALDH1A1 1326/4885PKM 2843/4885KDM4E 3119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.