SCHEMBL2385200

SCHEMBL2385200

COCOc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 9/20 0.82
MAPT P10636 6/20 0.82
BACE1 P56817 4/20 0.82
NFKB1 P19838 3/20 0.82
MMP9 P14780 3/20 0.82
CYP2D6 P10635 2/20 0.82
CYP2C9 P11712 2/20 0.82
TSHR P16473 2/20 0.82
HSD17B10 Q99714 2/20 0.82
ABCB1 P08183 2/20 0.82
AKR1B1 P15121 2/20 0.82
MAOA P21397 2/20 0.82
MAOB P27338 2/20 0.82
HDAC3 O15379 2/20 0.82
HDAC1 Q13547 2/20 0.82
HDAC2 Q92769 2/20 0.82
HDAC6 Q9UBN7 2/20 0.82
TOP2A P11388 2/20 0.82
ALOX5 P09917 2/20 0.82
STAT3 P40763 2/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28047873 1.00 APP (0.82) APPMAPTBACE1NFKB1MMP9
SCHEMBL31206160 1.00 APP (0.82) APPMAPTBACE1NFKB1MMP9
Curcumin SCHEMBL29358937 0.90 APP (1.00) APPMAPTBACE1NFKB1MMP9
Curcumin SCHEMBL17629819 0.90 APP (1.00) APPMAPTBACE1NFKB1MMP9
Curcumin SCHEMBL29355906 0.90 APP (1.00) APPMAPTBACE1NFKB1MMP9
Curcumin SCHEMBL8440 0.90 APP (1.00) APPMAPTBACE1NFKB1MMP9
Curcumin SCHEMBL17629818 0.90 APP (1.00) APPMAPTBACE1NFKB1MMP9
Curcumin SCHEMBL8336603 0.90 APP (1.00) APPMAPTBACE1NFKB1MMP9
Curcumin SCHEMBL2804734 0.90 APP (1.00) APPMAPTBACE1NFKB1MMP9
Curcumin SCHEMBL6901740 0.90 APP (1.00) APPMAPTBACE1NFKB1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114096155-B Animal food composition 马斯公司 2024-11-22 CN claimed
US-20220378810-A1 ANIMAL FOOD COMPOSITION MARS, INCORPORATED (US) 2022-12-01 US claimed
EP-3993633-A1 ANIMAL FOOD COMPOSITION Mars Incorporated (US) 2022-05-11 EP claimed
CN-114096155-A Animal food composition 马斯公司 2022-02-25 CN claimed
WO-2021229603-A2 FORMULATION OF PURE DIMETHOXY CURCUMIN-HUMAN SERUM ALBUMIN AND A PROCESS FOR THE PREPARATION THEREOF SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY (IN) 2021-11-18 WO claimed
WO-2021003280-A1 ANIMAL FOOD COMPOSITION MARS, INCORPORATED (US) 2021-01-07 WO claimed
CN-108404142-B Magnetic resonance imaging nano carrier, nano drug-loading system and preparation method thereof 暨南大学 2020-01-17 CN claimed
CN-108289476-A Hydration of animals 雀巢产品技术援助有限公司 2018-07-17 CN claimed
US-8535693-B2 Topical formulation(s) for the treatment of inflammation, skin and mucosal disorders and other diseases thereof Laila Pharmaceuticals Private Limited (US) 2013-09-17 US claimed
US-20110229532-A1 PROCESS FOR NANOEMULSIFICATION OF CURCUMIN AND DERIVATIVES OF CURCUMIN LAILA PHARMACEUTICALS PVT. LTD 2011-09-22 US claimed
CN-119700914-A Method for constructing neuroinflammation intervention animal model and screening active ingredients in turmeric dregs 广东药科大学 2025-03-28 CN disclosed
CN-114096155-B Animal food composition 马斯公司 2024-11-22 CN disclosed
CN-118955263-A Curcumin (curcumin) demethoxycurcumin and bisdemethylation preparation process of methoxy curcumin 江西丹霞生物科技股份有限公司 2024-11-15 CN disclosed
CN-118955263-A Curcumin (curcumin) demethoxycurcumin and bisdemethylation preparation process of methoxy curcumin 江西丹霞生物科技股份有限公司 2024-11-15 CN disclosed
EP-3768237-B1 LIVER PROTECTANT COMPOSITIONS AND THERAPEUTIC APPLICATIONS SAMI SABINSA GROUP LTD (IN) 2024-05-15 EP disclosed
CN-101227823-A Method for preparing tetrahydroxycurcumin and tetrahydroxycurcumin concentrated components from Curcuma rhizome extract GUKARAJI R G (IN) 2008-07-23 CN disclosed
US-20070243132-A1 Transdermal delivery of pharmaceutical agents APOLLO LIFE SCIENCES LIMITED (AU) 2007-10-18 US disclosed
EP-0839037-A4 BIOPROTECTANT COMPOSITION, METHOD OF USE AND EXTRACTION PROCESS OF CURCUMINOIDS SABINSA CORP (US) 1999-03-03 EP disclosed
EP-0839037-A1 BIOPROTECTANT COMPOSITION, METHOD OF USE AND EXTRACTION PROCESS OF CURCUMINOIDS Sabinsa Corporation (US) 1998-05-06 EP disclosed
WO-1997003674-A1 BIOPROTECTANT COMPOSITION, METHOD OF USE AND EXTRACTION PROCESS OF CURCUMINOIDS SABINSA CORPORATION (US) 1997-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110229532-A1 PROCESS FOR NANOEMULSIFICATION OF CURCUMIN AND DERIVATIVES OF CURCUMIN FABP4, LIPC, LIPA APP 2924/4885MAPT 1998/4885BACE1 2626/4885
US-20220378810-A1 ANIMAL FOOD COMPOSITION AGER, S100A4, TSLP APP 1660/4885MAPT 2123/4885BACE1 3933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.