Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864569 | 0.82 | LMNA (0.40) | TP53CES2CES1ALDH1A1HPGD | |
| SCHEMBL23864358 | 0.74 | KDM4C (0.39) | TP53ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL23864713 | 0.74 | KDM4E (0.36) | POLBALDH1A1HPGDLMNATSHR | |
| SCHEMBL23864607 | 0.74 | HPGD (0.49) | ALDH1A1HPGD | |
| SCHEMBL23864250 | 0.72 | LOXL2 (0.39) | TP53ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL23864419 | 0.72 | CRHBP (0.37) | TP53ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23864317 | 0.71 | CASP3 (0.36) | ALDH1A1HPGDLMNA | |
| SCHEMBL23864287 | 0.71 | CA2 (0.41) | POLBTP53ALDH1A1LMNA | |
| SCHEMBL55443 | 0.70 | CES2 (0.65) | POLBTP53CES2CES1ALDH1A1 | |
| SCHEMBL17187884 | 0.70 | CES2 (0.65) | POLBTP53CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |