Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 5/20 | 0.45 |
| ▸ | CDK2 | P24941 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31094224 | 0.75 | SLC2A1 (0.51) | CCNE1CDK2MAPTSLC2A1MEN1 | |
| SCHEMBL30234364 | 0.74 | CCNE1 (0.48) | CCNE1CDK2MAPTLMNAALDH1A1 | |
| SCHEMBL23867526 | 0.74 | CCNE1 (0.48) | CCNE1CDK2MAPTLMNAALDH1A1 | |
| SCHEMBL23867505 | 0.73 | HTR6 (0.44) | CCNE1CDK2MAPTSLC2A1MEN1 | |
| SCHEMBL23867649 | 0.73 | ALDH1A1 (0.52) | CCNE1CDK2MAPTSLC2A1LMNA | |
| SCHEMBL23867523 | 0.73 | SLC2A1 (0.49) | CCNE1CDK2MAPTSLC2A1LMNA | |
| SCHEMBL30979651 | 0.73 | SLC2A1 (0.51) | MAPTSLC2A1MEN1KMT2ALMNA | |
| SCHEMBL23867488 | 0.72 | LMNA (0.42) | CCNE1CDK2MAPTSLC2A1LMNA | |
| SCHEMBL23859942 | 0.72 | POLB (0.55) | MAPTTHRBSLC2A1TP53MEN1 | |
| SCHEMBL23867524 | 0.72 | HCRTR1 (0.52) | CCNE1CDK2MAPTSLC2A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023055763-A2 | SMALL MOLECULE INHIBITORS OF ONCOGENIC CHD1L WITH PRECLINICAL ACTIVITY AGAINST COLORECTRAL CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2023-04-06 | — | — | WO | disclosed |
| WO-2021195279-A2 | SMALL MOLECULE INHIBITORS OF ONCOGENIC CHD1L WITH PRECLINICAL ACTIVITY AGAINST COLORECTAL CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2021-09-30 | — | — | WO | disclosed |