Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912992 | 0.86 | LTA4H (0.53) | LTA4HLMNAHTTSMN1; SMN2HTR1A | |
| SCHEMBL23904680 | 0.76 | ADRA1A (0.53) | LMNAHTTSMN1; SMN2HTR1AADRA1D | |
| SCHEMBL23904679 | 0.76 | ADRA1A (0.53) | LMNAHTTSMN1; SMN2HTR1AADRA1D | |
| SCHEMBL2559961 | 0.76 | LMNA (0.59) | LTA4HLMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL12840659 | 0.76 | L3MBTL1 (0.61) | LMNAHTTSMN1; SMN2KDM4ES1PR3 | |
| SCHEMBL2655526 | 0.74 | THRA (0.51) | LMNAHTTSMN1; SMN2S1PR3MEN1 | |
| SCHEMBL23912884 | 0.73 | LMNA (0.42) | LMNAHTTSMN1; SMN2KDM4ES1PR3 | |
| SCHEMBL28288419 | 0.73 | MAPT (0.52) | LMNAHTTSMN1; SMN2KDM4ES1PR3 | |
| SCHEMBL2350644 | 0.72 | AR (0.47) | LMNAHTTSMN1; SMN2KDM4ES1PR3 | |
| SCHEMBL18902791 | 0.71 | HTR1B (0.57) | LMNAHTTHTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892615-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN | Minakem (FR) | 2021-10-13 | — | — | EP | disclosed |