Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310737 | 0.83 | HTR1A (0.53) | ALDH1A1KDM4EGAAMAPTMEN1 | |
| SCHEMBL2392804 | 0.82 | TTR (0.41) | ALDH1A1KDM4EGAACYP3A4MAPT | |
| SCHEMBL9515763 | 0.78 | DPEP1 (0.46) | ALDH1A1CYP3A4PPARGPSEN1PSEN2 | |
| SCHEMBL6561672 | 0.76 | PKM (0.53) | ALDH1A1KDM4EGAACYP1A2CYP3A4 | |
| SCHEMBL31302634 | 0.76 | PKM (0.53) | ALDH1A1KDM4EGAACYP1A2CYP3A4 | |
| SCHEMBL2394287 | 0.76 | PKM (0.53) | ALDH1A1KDM4EGAACYP1A2CYP3A4 | |
| SCHEMBL9515238 | 0.76 | TBXAS1 (0.43) | ALDH1A1CYP3A4CYP2C19PPARGPSEN1 | |
| SCHEMBL9515243 | 0.76 | TBXAS1 (0.43) | ALDH1A1CYP3A4CYP2C19PPARGPSEN1 | |
| SCHEMBL2388960 | 0.75 | BACE1 (0.46) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL2555923 | 0.74 | TRPA1 (0.55) | KDM4EPKMMEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |