Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388960 | 0.82 | BACE1 (0.46) | KMT2ATBXAS1MEN1ESR1GRIK1 | |
| SCHEMBL2391722 | 0.82 | ALDH1A1 (0.44) | KMT2ATBXAS1GAAALDH1A1MEN1 | |
| SCHEMBL9515763 | 0.81 | DPEP1 (0.46) | TBXAS1ALDH1A1GRIK1EPHX2CYP3A4 | |
| SCHEMBL2389163 | 0.81 | CYP2C9 (0.46) | TTRKMT2ATBXAS1ALDH1A1MEN1 | |
| SCHEMBL9515238 | 0.79 | TBXAS1 (0.43) | TBXAS1ALDH1A1ESR1GRIK1EPHX2 | |
| SCHEMBL9515243 | 0.79 | TBXAS1 (0.43) | TBXAS1ALDH1A1ESR1GRIK1EPHX2 | |
| SCHEMBL2555923 | 0.78 | TRPA1 (0.55) | KMT2ATBXAS1MEN1KDM4EGRIK1 | |
| SCHEMBL2555924 | 0.78 | TRPA1 (0.55) | KMT2ATBXAS1MEN1KDM4EGRIK1 | |
| SCHEMBL2394287 | 0.77 | PKM (0.53) | KMT2AGAAALDH1A1MEN1MAPT | |
| SCHEMBL6561672 | 0.77 | PKM (0.53) | KMT2AGAAALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |