Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 6/20 | 0.68 |
| ▸ | CA2 known ✓ | P00918 | 6/20 | 0.68 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.46 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.46 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.46 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618266 | 1.00 | CA12 (0.68) | CA12CA2CA9MAPTRAB9A | |
| SCHEMBL646075 | 0.87 | TSHR (0.62) | CA12CA2CA9MAPTMEN1 | |
| SCHEMBL28999750 | 0.87 | TSHR (0.62) | CA12CA2CA9MAPTMEN1 | |
| SCHEMBL7766922 | 0.87 | TSHR (0.62) | CA12CA2CA9MAPTMEN1 | |
| Potassium Ion SCHEMBL28275691 | 0.84 | TSHR (0.59) | CA12CA2CA9MAPTMEN1 | |
| SCHEMBL30460591 | 0.84 | TSHR (0.59) | CA12CA2CA9MAPTMEN1 | |
| Water SCHEMBL2045997 | 0.84 | TSHR (0.59) | CA12CA2CA9MAPTMEN1 | |
| Water SCHEMBL4384703 | 0.84 | TSHR (0.59) | CA12CA2CA9MAPTMEN1 | |
| SCHEMBL11323350 | 0.83 | CA12 (0.73) | CA12CA2CA9MAPTRAB9A | |
| Formaldehyde SCHEMBL9472914 | 0.82 | TSHR (0.56) | CA12CA2CA9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383170-A1 | FLEXIBLE AND SMART WOOD WITH RESPONSIVE FUNCTION, PREPARATION METHOD THEREOF AND ACTUATOR | NANJING FORESTRY UNIVERSITY (CN) | 2024-11-21 | — | — | US | claimed |
| CN-115554267-A | Pectin-based ultraviolet light response type nano carrier and preparation method thereof | 南京医科大学康达学院 | 2023-01-03 | — | — | CN | claimed |
| CN-111187408-A | Method for synthesizing polyamino acid with photoresponse characteristic | 金陵科技学院 | 2020-05-22 | — | — | CN | claimed |
| EP-1515144-B2 | METHOD OF ASSAY WITH SULFONIC ACID COMPOUND AND NITRO COMPOUND | ARKRAY INC (JP) | 2013-04-24 | — | — | EP | claimed |
| US-8021855-B2 | Method of decomposing protein with sulfonic acid compound | ARKRAY INC. (JP) | 2011-09-20 | — | — | US | claimed |
| EP-1515144-B1 | METHOD OF ASSAY WITH SULFONIC ACID COMPOUND AND NITRO COMPOUND | ARKRAY INC (JP) | 2009-10-14 | — | — | EP | claimed |
| US-7354732-B2 | Method of assay with sulfonic acid compound and nitro compound | ARKRAY, INC. (JP) | 2008-04-08 | — | — | US | claimed |
| US-20050260735-A1 | Method of decomposing protein with sulfonic acid compound | ARKRAY, INC. (JP) | 2005-11-24 | — | — | US | claimed |
| US-20050221415-A1 | Method of assay with sulfonic acid compound and nitro compound | ARKRAY, INC. (JP) | 2005-10-06 | — | — | US | claimed |
| EP-1522593-A1 | METHOD OF DECOMPOSING PROTEIN WITH SULFONIC ACID COMPOUND | ARKRAY, Inc. (JP) | 2005-04-13 | — | — | EP | claimed |
| EP-1515144-A1 | METHOD OF ASSAY WITH SULFONIC ACID COMPOUND AND NITRO COMPOUND | ARKRAY, Inc. (JP) | 2005-03-16 | — | — | EP | claimed |
| JP-4293969-A | — | — | None | — | — | JP | disclosed |
| US-20250221408-A1 | COMPOSITION | EARTH CORPORATION (JP) | 2025-07-10 | — | — | US | disclosed |
| CN-113993854-B | Luminescent compound or salt thereof, and polarized light emitting element, polarized light emitting panel and display device using the same | 日本化药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-119677819-A | Azo compound or salt thereof, and polarizing film, polarizing plate and liquid crystal display device each containing the same | 日本化药株式会社 | 2025-03-21 | — | — | CN | disclosed |
| WO-1999045389-A2 | LIGAND SCREENING AND DESIGN BY X-RAY CRYSTALLOGRAPHY | ABBOTT LAB (US) | 1999-09-10 | — | — | WO | disclosed |
| WO-1999045379-A2 | LIGAND SCREENING AND DESIGN BY X-RAY CRYSTALLOGRAPHY | ABBOTT LABORATORIES (US) | 1999-09-10 | — | — | WO | disclosed |
| JP-H04293969-A | LIQUID COMPOSITION OF DIRECT DYE | NIPPON KAYAKU CO LTD | 1992-10-19 | — | — | JP | disclosed |
| US-4227879-A | ISOLATING THE DIAZONIUM SALT OF P-(P-AMINOPHENYL)AZO BENZENESULFONIC ACID AND COUPLING WITH 6-AMINO-1-NAPHTHOL-3-SULFONIC ACID | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |
| US-4082742-A | PROCESS FOR PREPARING AN AQUEOUS DISAZO DYE CONCENTRATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250221408-A1 | COMPOSITION | GGPS1, PGGT1B, HBG2 | CA12 2951/4885CA2 2673/4885CA1 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.