SCHEMBL23948594

SCHEMBL23948594

CCOC(=O)C1(C)CN(c2cc(F)cc(F)c2)C1=O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.37
METAP2 P50579 1/20 0.34
CHRM1 P11229 1/20 0.34
KMT2A Q03164 3/20 0.33
ALOX15 P16050 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
P2RY1 P47900 1/20 0.33
GRM5 P41594 1/20 0.33
ADAMTS5 Q9UNA0 1/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32
XPO1 O14980 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23925111 0.85 L3MBTL1 (0.40) OPRM1KMT2AL3MBTL1LMNAMEN1
SCHEMBL23949222 0.80 SMN1; SMN2 (0.38) METAP2L3MBTL1ADAMTS5RAB9APOLB
SCHEMBL31128660 0.79 ADAMTS5 (0.36) OPRM1METAP2KMT2AALOX15L3MBTL1
SCHEMBL23948595 0.72 OPRM1 (0.36) OPRM1CHRM1KMT2AGRM5ADAMTS5
SCHEMBL21777587 0.72 F10 (0.49) OPRM1METAP2KMT2AL3MBTL1LMNA
SCHEMBL11269738 0.71 ALDH1A1 (0.35) OPRM1KMT2AMEN1TSHRPOLB
SCHEMBL23949223 0.71 TSHR (0.34) METAP2KMT2AADAMTS5MEN1TSHR
SCHEMBL23949224 0.71 TSHR (0.34) METAP2KMT2AADAMTS5MEN1TSHR
SCHEMBL23925288 0.70 ITGB3 (0.36) METAP2ADAMTS5TSHR
SCHEMBL23925287 0.70 ITGB3 (0.36) METAP2ADAMTS5TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230148598-A1 BETA-LACTAMS AND THEIR USE AS HERBICIDES BASF SE (DE) 2023-05-18 US disclosed
US-20230148598-A1 BETA-LACTAMS AND THEIR USE AS HERBICIDES BASF SE (DE) 2023-05-18 US disclosed
CN-115279735-A Beta-lactams and their use as herbicides 巴斯夫欧洲公司 2022-11-01 CN disclosed
WO-2021209268-A1 BETA-LACTAMS AND THEIR USE AS HERBICIDES BASF SE (DE) 2021-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230148598-A1 BETA-LACTAMS AND THEIR USE AS HERBICIDES POLL, HDHD5, GLRB OPRM1 277/4885METAP2 2887/4885CHRM1 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.