SCHEMBL2396787

SCHEMBL2396787

CCC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CCC4CC(O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.83

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.83
KMT2A Q03164 2/20 0.83
ALDH1A1 P00352 2/20 0.83
USP2 O75604 1/20 0.83
MAPT P10636 1/20 0.83
ALOX15 P16050 1/20 0.83
DHCR24 Q15392 11/20 0.72
TRPV1 Q8NER1 1/20 0.63
THRB P10828 1/20 0.47
OSBP P22059 2/20 0.44
RORC P51449 2/20 0.44
NR1H3 Q13133 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12869826 1.00 MEN1 (0.83) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL12869831 0.92 MEN1 (0.83) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL28606202 0.91 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL1957035 0.91 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL5571689 0.91 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL25035233 0.91 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL15529878 0.91 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL187737 0.91 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL22099724 0.91 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT
SCHEMBL14360754 0.91 USP2 (1.00) MEN1KMT2AALDH1A1USP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2377874-B1 Compositions comprising a lophenol MORINAGA MILK INDUSTRY CO LTD (JP) 2019-01-23 EP disclosed
US-8470807-B2 Antioxidant MORINAGA MILK INDUSTRY CO., LTD. (JP) 2013-06-25 US disclosed
EP-2377874-A1 ANTIOXIDANT Morinaga Milk Industry Co., Ltd. (JP) 2011-10-19 EP disclosed
US-20110212931-A1 ANTIOXIDANT MORINAGA MILK INDUSTRY CO., LTD. (JP) 2011-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212931-A1 ANTIOXIDANT GPX4, GPX1, LPO MEN1 4817/4885KMT2A 3798/4885ALDH1A1 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.