SCHEMBL23973

SCHEMBL23973

[c]1cc2ncccc2c2ncccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.48
KDM4E B2RXH2 7/20 0.45
MAPT P10636 6/20 0.45
HSP90AA1 P07900 7/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
NPC1 O15118 2/20 0.41
CYP3A4 P08684 3/20 0.37
HTT P42858 4/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
HIF1A Q16665 2/20 0.36
HSP90AB1 P08238 2/20 0.36
BLM P54132 1/20 0.36
CCR1 P32246 3/20 0.35
CCR8 P51685 3/20 0.35
TP53 P04637 2/20 0.35
MMP9 P14780 2/20 0.35
ALOX15 P16050 2/20 0.35
MMP13 P45452 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2517518 0.82 MAPT (0.52) LMNAKDM4EMAPTHSP90AA1L3MBTL1
SCHEMBL2519049 0.79 CCR1 (0.43) LMNAKDM4EMAPTHSP90AA1L3MBTL1
SCHEMBL24065 0.78 LMNA (0.55) LMNAKDM4EMAPTHSP90AA1L3MBTL1
SCHEMBL2513089 0.77 LMNA (0.36) LMNAKDM4EMAPTHSP90AA1L3MBTL1
SCHEMBL17511885 0.73 KDM4E (0.45) LMNAKDM4EMAPTHSP90AA1L3MBTL1
SCHEMBL23991 0.73 MAPT (0.45) LMNAKDM4EMAPTHSP90AA1L3MBTL1
SCHEMBL25121 0.72 CCR1 (0.54) LMNAKDM4EMAPTHSP90AA1L3MBTL1
SCHEMBL17511892 0.72 MAPT (0.54) LMNAKDM4EMAPTHSP90AA1L3MBTL1
SCHEMBL2520862 0.72 LMNA (0.43) LMNAKDM4EMAPTHSP90AA1L3MBTL1
SCHEMBL2513044 0.72 ALDH1A1 (0.47) LMNAKDM4EMAPTHSP90AA1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 948 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49118-E1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-28 US claimed
CN-112390811-B Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-03-04 CN claimed
CN-114057711-A Anthracene ketone spiro derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-02-18 CN claimed
CN-107556298-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-12-21 CN claimed
CN-107586290-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-05-11 CN claimed
CN-112390811-A Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2021-02-23 CN claimed
CN-110551054-A maleimide derivative, and preparation method and application thereof TECHNICAL INST PHYSICS & CHEMISTRY CAS 2019-12-10 CN claimed
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-05-07 US claimed
EP-2213641-B1 FUSED AROMATIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO (JP) 2018-05-16 EP claimed
US-20180090685-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2018-03-29 US claimed
US-9660195-B2 Anthracene derivative having a phenanthryl group IDEMITSU KOSAN CO., LTD. (JP) 2017-05-23 US claimed
US-9527814-B2 Aromatic amine derivative, organic device material and hole-injection/transport material and organic electroluminescent element material each comprising the derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2016-12-27 US claimed
US-9324950-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-04-26 US claimed
US-20150214487-A1 9,10-Bis[2-(p-substituted phenyl)pyrimidin-4-yl] Anthracene Compounds, Methods of Preparing the Same, Organic Electroluminescent Devices and Organic Electroluminescent Display Apparatus BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-07-30 US claimed
US-8822041-B2 Anthracene derivatives, luminescent materials and organic electroluminescent devices IDEMITSU KOSAN CO., LTD. (JP) 2014-09-02 US claimed
US-20140103319-A1 ANTHRACENE DERIVATIVES, LUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2014-04-17 US claimed
US-20120112176-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US claimed
US-8101290-B2 Organic compound having electron-transporting and/or hole-blocking performance and its use and OLEDs comprising the compound TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) 2012-01-24 US claimed
US-20090102356-A1 NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) 2009-04-23 US claimed
US-20090043116-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2009-02-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180090685-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE SLC18A1, SLC18A2, AOC2 LMNA 3089/4885KDM4E 2498/4885MAPT 2683/4885
US-20090102356-A1 NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND SLCO4C1, SLCO1B1, SLCO2B1 LMNA 2530/4885KDM4E 3317/4885MAPT 670/4885
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 LMNA 3089/4885KDM4E 2498/4885MAPT 2683/4885
US-20090043116-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS PBRM1, BICRA, PARG LMNA 165/4885KDM4E 1711/4885MAPT 190/4885
US-20150214487-A1 9,10-Bis[2-(p-substituted phenyl)pyrimidin-4-yl] Anthracene Compounds, Methods of Preparing the Same, Organic Electroluminescent Devices and Organic Electroluminescent Display Apparatus P2RY10, P2RY4, APRT LMNA 1509/4885KDM4E 754/4885MAPT 1048/4885
US-20120112176-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME EML4, DDC, ALKBH2 LMNA 2124/4885KDM4E 136/4885MAPT 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.