SCHEMBL239741

SCHEMBL239741

C=C(C)Cc1cc(C(C)(C)c2ccc(OC)c(CC(=C)C)c2)ccc1OC

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.41
KLF10 Q13118 1/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP3A4 P08684 1/20 0.38
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 2/20 0.35
ESR1 P03372 1/20 0.34
CASP1 P29466 1/20 0.34
CACNA1B Q00975 1/20 0.34
HTT P42858 1/20 0.34
NR1H4 Q96RI1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10871992 0.82 ELANE (0.49) ELANEKLF10HSD17B10CYP3A4MTNR1A
SCHEMBL8964266 0.80 HSD17B10 (0.45) ELANEHSD17B10CYP3A4MEN1KMT2A
SCHEMBL1258536 0.78 KLF10 (0.62) KLF10HSD17B10CYP3A4MEN1KMT2A
SCHEMBL241385 0.78 ALOX15 (0.37) ELANEKLF10HSD17B10CYP3A4ALDH1A1
SCHEMBL19267931 0.78 TAAR1 (0.43) KLF10HSD17B10L3MBTL1MEN1KMT2A
SCHEMBL239070 0.77 CA2 (0.53) HSD17B10CYP3A4MTNR1AMTNR1BMEN1
SCHEMBL10874094 0.76 ELANE (0.39) ELANEKLF10MEN1KMT2AALDH1A1
SCHEMBL238989 0.75 GABRA1 (0.52) CYP3A4ALDH1A1
SCHEMBL12438742 0.74 TSHR (0.44) MTNR1AMTNR1BL3MBTL1
SCHEMBL11016520 0.73 ELANE (0.37) ELANEKLF10L3MBTL1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US claimed
US-9512333-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2016-12-06 US disclosed
EP-2417168-B1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS HUNTSMAN ADV MAT AMERICAS INC (US) 2014-11-26 EP disclosed
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
US-20130231021-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-09-05 US disclosed
US-8445699-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-05-21 US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 WO disclosed
EP-2417168-A1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS Huntsman Advanced Materials Americas LLC (US) 2012-02-15 EP disclosed
US-20120003892-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions Huntsman Advanced Materials Americans LLC (US) 2012-01-05 US disclosed
US-5240981-A Blend with alkenylphenol, tribromophenylmaleimide, free radical catalyst, and phenothiazine derivative CIBA-GEIGY CORPORATION (US) 1993-08-31 US disclosed
US-5183869-A Bismaleimides, 2-6-dialkyl-4-allylphenols or 2,6-dialkyl-4-allylphenol allyl ethers; crosslinking CIBA-GEIGY CORPORATION (US) 1993-02-02 US disclosed
EP-0517656-A2 Fire-protected polyimide composition CIBA-GEIGY AG (CH) 1992-12-09 EP disclosed
EP-0457732-A1 Curable compositions CIBA-GEIGY AG (CH) 1991-11-21 EP disclosed
EP-0385937-A1 Curable blends based on aromatic bismaleinimides CIBA-GEIGY AG (CH) 1990-09-05 EP disclosed
EP-0348345-A2 Solution stable polyimide resin systems CIBA-GEIGY AG (CH) 1989-12-27 EP disclosed
EP-0227598-B1 STABLE COMPOSITIONS CONTAINING IMIDES CIBA-GEIGY AG (CH) 1989-08-02 EP disclosed
EP-0235084-A2 Hot-curable compositions containing substituted bicyclo[2,2,1]hept-5-ene-2,3 imides of dicarboxylic acids and polymalein imide CIBA-GEIGY AG (CH) 1987-09-02 EP disclosed
US-4678849-A PREPREGS, COMPOSITES, COATINGS CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
EP-0227598-A1 Stable compositions containing imides CIBA-GEIGY AG (CH) 1987-07-01 EP disclosed