Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239070 | 0.82 | CA2 (0.53) | HSD17B10CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL5932077 | 0.81 | CFD (0.51) | HSD17B10ALOX5CYP3A4ELANEALDH1A1 | |
| SCHEMBL239741 | 0.80 | ELANE (0.41) | HSD17B10CYP3A4ELANEALDH1A1MEN1 | |
| SCHEMBL5719348 | 0.77 | LMNA (0.56) | CYP3A4ALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL1257364 | 0.75 | GABRA1 (0.52) | GABRA1GABRB2ALOX5CNR2HSD17B1 | |
| SCHEMBL12325012 | 0.74 | HSD17B1 (0.59) | HSD17B10GABRA1GABRB2ALOX5CNR2 | |
| SCHEMBL9512053 | 0.73 | KDM4E (0.62) | HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL9623642 | 0.73 | GAA (0.51) | HSD17B10CYP3A4ELANEALDH1A1MAPT | |
| SCHEMBL9512050 | 0.73 | KDM4E (0.62) | HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL13907997 | 0.73 | ACHE (0.48) | CYP3A4ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348345-B1 | Solution stable polyimide resin systems | CIBA GEIGY AG (CH) | 1996-02-14 | — | — | EP | disclosed |
| EP-0457732-B1 | Curable compositions | CIBA GEIGY AG (CH) | 1995-03-01 | — | — | EP | disclosed |
| EP-0585205-A2 | Curable compositions of furylallylnovolaks and bismaleimides | CIBA-GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| US-5183869-A | Bismaleimides, 2-6-dialkyl-4-allylphenols or 2,6-dialkyl-4-allylphenol allyl ethers; crosslinking | CIBA-GEIGY CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |
| EP-0457732-A1 | Curable compositions | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |
| EP-0348345-A2 | Solution stable polyimide resin systems | CIBA-GEIGY AG (CH) | 1989-12-27 | — | — | EP | disclosed |
| EP-0227598-B1 | STABLE COMPOSITIONS CONTAINING IMIDES | CIBA-GEIGY AG (CH) | 1989-08-02 | — | — | EP | disclosed |
| EP-0235084-A2 | Hot-curable compositions containing substituted bicyclo[2,2,1]hept-5-ene-2,3 imides of dicarboxylic acids and polymalein imide | CIBA-GEIGY AG (CH) | 1987-09-02 | — | — | EP | disclosed |