Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24023157 | 0.88 | GAA (0.47) | HDAC6HDAC2HDAC1HDAC8TLR9 | |
| SCHEMBL24023216 | 0.83 | PLK1 (0.44) | HDAC6HDAC2HDAC3HDAC1HDAC8 | |
| SCHEMBL19391346 | 0.81 | HDAC2 (0.53) | HDAC6HDAC2HDAC8CYP2C9MEN1 | |
| SCHEMBL105171 | 0.79 | HDAC6 (0.59) | HDAC6HDAC2HDAC1HDAC8CYP2C9 | |
| SCHEMBL24252035 | 0.76 | HPGD (0.47) | HDAC6HDAC2HDAC8MEN1KMT2A | |
| SCHEMBL19369014 | 0.76 | CRBN (0.54) | HDAC6HDAC8ROCK2CYP1A2CYP2C9 | |
| SCHEMBL8676137 | 0.75 | LMNA (0.48) | HDAC6MEN1KMT2ANPC1RAB9A | |
| SCHEMBL19346306 | 0.74 | HTT (0.48) | HDAC6HDAC2HDAC1HDAC8TLR8 | |
| SCHEMBL24807366 | 0.74 | KIF11 (0.45) | HDAC6HDAC2HDAC3HDAC1HDAC8 | |
| SCHEMBL3110462 | 0.73 | CHEK2 (0.41) | HDAC6HDAC2HDAC8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174281-B1 | Modified nucleotides and uses thereof | Singular Genomics Systems, Inc. (US) | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174281-B1 | Modified nucleotides and uses thereof | NUDT1, RNMT, ADAR | HDAC6 2599/4885HDAC2 4317/4885HDAC3 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.