Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 6/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348377 | 0.90 | HTR1A (0.49) | GPR84MTNR1AMTNR1BMPOSLC6A4 | |
| SCHEMBL1969257 | 0.84 | HTR6 (0.62) | GPR84MTNR1AMTNR1BMPOSLC6A4 | |
| SCHEMBL1970036 | 0.84 | MPO (0.70) | MTNR1AMTNR1BMPOSLC6A4HTR6 | |
| SCHEMBL2409563 | 0.81 | HTR1A (0.54) | MPOSLC6A4HTR2BHTR6HTR1A | |
| SCHEMBL1976170 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BMPOSLC6A4HTR6 | |
| SCHEMBL2406261 | 0.78 | MTNR1A (0.60) | GPR84MTNR1AMTNR1BMPOSLC6A4 | |
| SCHEMBL2405163 | 0.78 | GPR84 (0.54) | GPR84MTNR1AMTNR1BSLC6A4HTR6 | |
| SCHEMBL1971950 | 0.78 | HTR2A (0.56) | MTNR1AMTNR1BHTR6HTR1ABCHE | |
| SCHEMBL1968351 | 0.77 | BCHE (0.67) | MTNR1ASLC6A4HTR1ABCHE | |
| SCHEMBL1969255 | 0.76 | MPO (0.57) | GPR84MTNR1AMTNR1BMPOSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | GPR84 73/4885MTNR1A 23/4885MTNR1B 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.