Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10258195 | 0.89 | NLRP3 (0.43) | L3MBTL1KMT2AP2RX7ALDH1A1SMN1; SMN2 | |
| SCHEMBL14499487 | 0.84 | P2RX7 (0.44) | MEN1KMT2AP2RX7HSD17B10 | |
| SCHEMBL14499486 | 0.82 | P2RX7 (0.39) | L3MBTL1MEN1KMT2AP2RX7ALDH1A1 | |
| SCHEMBL13949103 | 0.81 | P2RX7 (0.45) | P2RX7ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL14223949 | 0.78 | MCL1 (0.44) | L3MBTL1ALDH1A1SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL14223951 | 0.77 | ESR1 (0.48) | L3MBTL1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL706766 | 0.76 | ALDH1A1 (0.51) | L3MBTL1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31074056 | 0.76 | PKM (0.43) | L3MBTL1KMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL22539808 | 0.76 | P2RX7 (0.43) | MEN1KMT2AP2RX7SMN1; SMN2CYP1A2 | |
| SCHEMBL18552880 | 0.75 | LMNA (0.45) | L3MBTL1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252559-B2 | Methods and systems for selective fluorination of organic molecules | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-08-28 | — | — | US | disclosed |
| US-8026085-B2 | Methods and systems for selective fluorination of organic molecules | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2011-09-27 | — | — | US | disclosed |
| US-20090209010-A1 | METHODS AND SYSTEMS FOR SELECTIVE FLUORINATION OF ORGANIC MOLECULES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-08-20 | — | — | US | disclosed |
| US-20090061471-A1 | Methods and systems for selective fluorination of organic molecules | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2009-03-05 | — | — | US | disclosed |