Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045782 | 0.78 | NPC1 (0.30) | RAB9ANPC1 | |
| SCHEMBL24045765 | 0.73 | FPR2 (0.48) | HPGDLMNAGFERPDK2ALDH1A1 | |
| SCHEMBL24045801 | 0.71 | MEN1 (0.53) | HPGDMEN1LMNAKMT2AGFER | |
| SCHEMBL24093571 | 0.71 | RAB9A (0.53) | RAB9ANPC1HPGDMEN1LMNA | |
| SCHEMBL18955154 | 0.69 | PIP4K2A (0.51) | HPGDMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL27409503 | 0.69 | ALDH1A1 (0.59) | RAB9ANPC1HPGDMEN1LMNA | |
| SCHEMBL76559 | 0.69 | ALDH1A1 (0.59) | RAB9ANPC1HPGDMEN1LMNA | |
| SCHEMBL1691497 | 0.68 | SMN1; SMN2 (0.54) | RAB9ANPC1HPGDLMNAALDH1A1 | |
| SCHEMBL26779861 | 0.68 | ALDH1A1 (0.64) | RAB9ANPC1HPGDMEN1LMNA | |
| Hydrochloric Acid SCHEMBL7459714 | 0.67 | ALDH1A1 (0.58) | RAB9ANPC1HPGDMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414227-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-24 | — | — | EP | disclosed |