Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045801 | 0.78 | MEN1 (0.53) | HPGDMEN1LMNAKMT2AGFER | |
| SCHEMBL24093510 | 0.76 | FPR2 (0.45) | — | |
| SCHEMBL24337010 | 0.76 | RAB9A (0.39) | RAB9ANPC1HPGDMEN1LMNA | |
| SCHEMBL26779861 | 0.74 | ALDH1A1 (0.64) | RAB9ANPC1HPGDMEN1LMNA | |
| SCHEMBL24093648 | 0.73 | FPR2 (0.43) | — | |
| SCHEMBL11142367 | 0.72 | ALDH1A1 (0.74) | RAB9ANPC1HPGDALDH1A1CYP1A2 | |
| SCHEMBL24045765 | 0.71 | FPR2 (0.48) | HPGDLMNAGFERALDH1A1PDK2 | |
| SCHEMBL24045893 | 0.71 | RAB9A (0.44) | RAB9ANPC1HPGDMEN1LMNA | |
| SCHEMBL136476 | 0.70 | ALDH1A1 (0.67) | RAB9ANPC1HPGDMEN1LMNA | |
| SCHEMBL4468734 | 0.70 | ALDH1A1 (0.57) | RAB9ANPC1HPGDMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3762380-B1 | PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-12-15 | — | — | EP | disclosed |