SCHEMBL24065356

SCHEMBL24065356

CCOCCOCCOc1ccc(-c2nc3ccccc3[nH]2)cc1OCCOCCOCC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.51
AMY1A P0DUB6 1/20 0.51
CHRNB4 P30926 1/20 0.48
CHRNA3 P32297 1/20 0.48
CHRNA7 P36544 1/20 0.48
ACHE P22303 2/20 0.48
NPC1 O15118 6/20 0.48
RAB9A P51151 6/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
MEN1 O00255 1/20 0.48
POLB P06746 1/20 0.48
KMT2A Q03164 1/20 0.48
PKM P14618 4/20 0.47
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 4/20 0.47
HPGD P15428 2/20 0.47
NFKB1 P19838 2/20 0.47
NFKB2 Q00653 2/20 0.47
RELA Q04206 2/20 0.47
HPSE Q9Y251 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7391707 0.77 GUSB (0.71) MAPTNPC1RAB9ASMN1; SMN2MEN1
SCHEMBL22488596 0.76 AMY1A (0.53) MAPTAMY1ANPC1RAB9ASMN1; SMN2
SCHEMBL12470605 0.75 ALOX5 (0.70) MAPTAMY1ANPC1RAB9ASMN1; SMN2
SCHEMBL7399276 0.74 HPSE (0.54) MAPTAMY1ANPC1RAB9ASMN1; SMN2
SCHEMBL6520239 0.74 PDE4A (0.67) MAPTAMY1ANPC1RAB9ASMN1; SMN2
SCHEMBL31027909 0.72 NPC1 (0.70) MAPTCHRNB4CHRNA3CHRNA7ACHE
SCHEMBL22452317 0.72 NPC1 (0.70) MAPTCHRNB4CHRNA3CHRNA7ACHE
SCHEMBL4175670 0.72 NPC1 (0.61) MAPTAMY1ANPC1RAB9ASMN1; SMN2
SCHEMBL10845975 0.72 ALDH1A1 (0.55) MAPTNPC1RAB9ASMN1; SMN2MEN1
SCHEMBL16018033 0.71 GUSB (0.80) MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210373438-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2021-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210373438-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE RARA, RXRA, RAD54L MAPT 187/4885AMY1A 450/4885CHRNB4 4053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.