Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 11/20 | 0.35 |
| ▸ | PPME1 | Q9Y570 | 3/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411857 | 0.92 | NR3C1 (0.36) | NR3C1RORCPPME1GLO1SLC40A1 | |
| SCHEMBL2410874 | 0.90 | NFE2L2 (0.35) | — | |
| SCHEMBL4418740 | 0.88 | MET (0.41) | GLO1SLC40A1 | |
| SCHEMBL4425473 | 0.85 | HTR6 (0.33) | GRM5 | |
| SCHEMBL4419026 | 0.83 | MET (0.40) | GLO1SLC40A1 | |
| SCHEMBL2409994 | 0.83 | PLCG1 (0.33) | — | |
| SCHEMBL2408490 | 0.82 | HTR6 (0.35) | — | |
| SCHEMBL4425656 | 0.82 | MET (0.39) | — | |
| SCHEMBL2410027 | 0.80 | NTRK1 (0.31) | — | |
| SCHEMBL2414854 | 0.79 | KDR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |