Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 6/20 | 0.34 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410874 | 0.92 | NFE2L2 (0.35) | METNFE2L2KAT8HTR6ALDH1A1 | |
| SCHEMBL4419026 | 0.89 | MET (0.40) | METNFE2L2KAT8HTR6ELAVL1 | |
| SCHEMBL2408730 | 0.88 | NR3C1 (0.35) | GLO1SLC40A1 | |
| SCHEMBL2408490 | 0.83 | HTR6 (0.35) | METHTR6FGFR4ALDH1A1DRD2 | |
| SCHEMBL4425656 | 0.83 | MET (0.39) | METALDH1A1 | |
| Hydrochloric Acid SCHEMBL4416301 | 0.82 | MET (0.34) | METHTR6ALPLFGFR4 | |
| SCHEMBL1834071 | 0.81 | NFE2L2 (0.33) | METNFE2L2ALDH1A1 | |
| SCHEMBL2410027 | 0.81 | NTRK1 (0.31) | ALDH1A1 | |
| SCHEMBL2409435 | 0.81 | MET (0.43) | METNFE2L2KAT8HTR6GLO1 | |
| SCHEMBL4425473 | 0.80 | HTR6 (0.33) | HTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |