Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411005 | 0.90 | P2RX7 (0.35) | CTSACPB1CPB2 | |
| SCHEMBL1830978 | 0.72 | DYRK1A (0.35) | NAPRTMMP2MMP9MMP8MMP13 | |
| SCHEMBL2409335 | 0.71 | HTR2C (0.39) | CACNA1G | |
| SCHEMBL3700741 | 0.70 | PTGDR2 (0.34) | CTSAMMP2MMP9MMP8MMP13 | |
| SCHEMBL2192366 | 0.70 | DCTPP1 (0.31) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL476324 | 0.69 | COMT (0.35) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2194609 | 0.69 | MMP2 (0.30) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2410511 | 0.69 | ABCC9 (0.33) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2412156 | 0.68 | DCTPP1 (0.32) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2407099 | 0.68 | OPRM1 (0.32) | MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |