Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 6/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CPB1 | P15086 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409332 | 0.90 | CTSA (0.32) | CTSACPB1CPB2 | |
| SCHEMBL2409138 | 0.73 | ITGB2 (0.41) | ITGB2ICAM1ITGALSMN1; SMN2LMNA | |
| SCHEMBL2411007 | 0.71 | HTR2C (0.38) | P2RX7ALDH1A1L3MBTL1CPB2 | |
| SCHEMBL2412415 | 0.71 | PTGDR2 (0.34) | ITGB2ICAM1ITGALSMN1; SMN2 | |
| SCHEMBL2412156 | 0.71 | DCTPP1 (0.32) | — | |
| SCHEMBL2408861 | 0.69 | FPR1 (0.33) | — | |
| SCHEMBL2412428 | 0.68 | NFE2L2 (0.35) | — | |
| SCHEMBL1830978 | 0.67 | DYRK1A (0.35) | ITGB2ICAM1ITGAL | |
| SCHEMBL1156674 | 0.66 | ACLY (0.38) | ITGB2ICAM1ITGAL | |
| SCHEMBL2192366 | 0.65 | DCTPP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |