Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 12/20 | 0.40 |
| ▸ | MMP13 | P45452 | 7/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409439 | 0.90 | MMP2 (0.33) | MMP13HTR6MMP2MMP9MMP8 | |
| SCHEMBL2194752 | 0.86 | MMP2 (0.33) | MMP13MMP2MMP9MMP8 | |
| SCHEMBL2409033 | 0.85 | PTGDR2 (0.32) | — | |
| SCHEMBL2415885 | 0.85 | ADAMTS4 (0.31) | ADAMTS4 | |
| SCHEMBL2411039 | 0.84 | ABCC9 (0.34) | MMP13HTR6MMP2MMP9MMP8 | |
| SCHEMBL2412351 | 0.84 | MET (0.40) | MMP13HTR6MMP2MMP9MMP8 | |
| SCHEMBL4570000 | 0.84 | MMP2 (0.36) | MMP13RORCMMP2MMP9MMP8 | |
| SCHEMBL2411930 | 0.83 | EPHX2 (0.33) | — | |
| SCHEMBL2415904 | 0.83 | IDE (0.32) | MMP13MMP2MMP9MMP8 | |
| SCHEMBL2407582 | 0.83 | MET (0.38) | MMP13MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |