Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154389 | 0.78 | CYP3A4 (0.47) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL11238026 | 0.77 | CYP3A4 (0.53) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL5146946 | 0.74 | CYP3A4 (0.50) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL1774407 | 0.74 | CYP3A4 (0.50) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL7517260 | 0.72 | CYP3A4 (0.47) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL113870 | 0.72 | CHEK1 (0.60) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL16931972 | 0.72 | CYP3A4 (0.47) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL15268120 | 0.72 | CHEK1 (0.48) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL7550030 | 0.72 | CYP3A4 (0.47) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL29707613 | 0.72 | CHEK1 (0.60) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874418-B | Conjugated polymer based on trifluoromethyl substituted quinoxaline, and preparation method and application thereof | 广东聚石科技研究有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-114874418-A | Conjugated polymer based on trifluoromethyl substituted quinoxaline and preparation method and application thereof | 广东聚石科技研究有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-114874418-B | Conjugated polymer based on trifluoromethyl substituted quinoxaline, and preparation method and application thereof | 广东聚石科技研究有限公司 | 2023-12-19 | — | — | CN | disclosed |
| US-11446294-B2 | Non-platinum-based anti-cancer compounds for use in targeted chemotherapy | LU QING BIN (CA) | 2022-09-20 | — | — | US | disclosed |
| CN-114874418-A | Conjugated polymer based on trifluoromethyl substituted quinoxaline and preparation method and application thereof | 广东聚石科技研究有限公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-3578176-A1 | NON-PLATINUM-BASED ANTI-CANCER COMPOUNDS FOR USE IN TARGETED CHEMOTHERAPY | Lu, Qing-Bin (CA) | 2019-12-11 | — | — | EP | disclosed |
| EP-2935215-B1 | RADIOSENSITIZER COMPOUNDS FOR USE IN COMBINATION WITH RADIATION | LU QING BIN (CA) | 2019-11-13 | — | — | EP | disclosed |
| EP-3055287-B1 | NON-PLATINUM-BASED ANTI-CANCER COMPOUNDS FOR USE IN TARGETED CHEMOTHERAPY | LU QING BIN (CA) | 2019-11-06 | — | — | EP | disclosed |
| US-10463662-B2 | Non-platinum-based anti-cancer compounds for use in targeted chemotherapy | LU QING BIN (CA) | 2019-11-05 | — | — | US | disclosed |
| US-9655965-B2 | Radiosensitizer compounds for use in combination with radiation | Lu qing-bin (CA) | 2017-05-23 | — | — | US | disclosed |
| US-20160235743-A1 | NON-PLATINUM-BASED ANTI-CANCER COMPOUNDS FOR USE IN TARGETED CHEMOTHERAPY | Lu qing-bin (CA) | 2016-08-18 | — | — | US | disclosed |
| US-20150343059-A1 | RADIOSENSITIZER COMPOUNDS FOR USE IN COMBINATION WITH RADIATION | Lu qing-bin (CA) | 2015-12-03 | — | — | US | disclosed |
| EP-2935215-A1 | RADIOSENSITIZER COMPOUNDS FOR USE IN COMBINATION WITH RADIATION | Lu, Qing-Bin (CA) | 2015-10-28 | — | — | EP | disclosed |
| WO-2015051458-A1 | NON-PLATIMUN-BASED ANTI-CANCER COMPOUNDS FOR USE IN TARGETED CHEMOTHERAPY | Lu qing-bin (CA) | 2015-04-16 | — | — | WO | disclosed |
| WO-2014094178-A1 | RADIOSENSITIZER COMPOUNDS FOR USE IN COMBINATION WITH RADIATION | Lu qing-bin (CA) | 2014-06-26 | — | — | WO | disclosed |
| US-20120101243-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | UNITED STATES DEPARTMENT OF ENERGY | 2012-04-26 | — | — | US | disclosed |
| US-8106393-B2 | Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-31 | — | — | US | disclosed |
| US-20120004384-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | UNITED STATES DEPARTMENT OF ENERGY | 2012-01-05 | — | — | US | disclosed |
| US-7919770-B2 | Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-04-05 | — | — | US | disclosed |
| US-20110015388-A1 | Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom | UNITED STATES DEPARTMENT OF ENERGY | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10463662-B2 | Non-platinum-based anti-cancer compounds for use in targeted chemotherapy | TOP2B, POLR2B, RB1 | CYP3A4 2840/4885ALOX15 4660/4885CASP1 1806/4885 |
| US-20150343059-A1 | RADIOSENSITIZER COMPOUNDS FOR USE IN COMBINATION WITH RADIATION | RB1, ERCC2, RBBP7 | CYP3A4 2671/4885ALOX15 4579/4885CASP1 3330/4885 |
| US-20120004384-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | PNMT, HNMT, COMT | CYP3A4 164/4885ALOX15 1835/4885CASP1 4062/4885 |
| US-11446294-B2 | Non-platinum-based anti-cancer compounds for use in targeted chemotherapy | TOP2B, RB1, POLR2B | CYP3A4 2815/4885ALOX15 4611/4885CASP1 1928/4885 |
| US-20160235743-A1 | NON-PLATINUM-BASED ANTI-CANCER COMPOUNDS FOR USE IN TARGETED CHEMOTHERAPY | TOP2B, POLR2B, RB1 | CYP3A4 2840/4885ALOX15 4660/4885CASP1 1806/4885 |
| US-20120101243-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | PNMT, HNMT, COMT | CYP3A4 164/4885ALOX15 1835/4885CASP1 4062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.