SCHEMBL241384

SCHEMBL241384

C=CCc1cc(C(C)(C)c2cc(CC=C)c(OC)c(CC=C)c2)cc(CC=C)c1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.46
ALOX15 P16050 3/20 0.46
POLB P06746 3/20 0.40
ALDH1A1 P00352 7/20 0.38
PPARG P37231 1/20 0.38
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
ALOX12 P18054 1/20 0.37
ALOX5 P09917 3/20 0.36
GABRA1 P14867 3/20 0.36
GABRB2 P47870 3/20 0.36
CNR2 P34972 2/20 0.36
DHFR P00374 1/20 0.36
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
AR P10275 1/20 0.35
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20226269 0.81 HTT (0.36) CYP3A4ALOX15ALDH1A1SMN1; SMN2MAPK1
SCHEMBL8451613 0.79 CYP3A4 (0.51) CYP3A4ALOX15POLBALDH1A1PPARG
SCHEMBL238989 0.79 GABRA1 (0.52) CYP3A4ALOX15ALDH1A1PPARGPPARD
SCHEMBL240977 0.78 ALOX15 (0.53) CYP3A4ALOX15POLBALDH1A1TSHR
SCHEMBL770139 0.78 ALDH1A1 (0.50) CYP3A4ALOX15POLBALDH1A1PPARG
SCHEMBL5879482 0.78 CYP3A4 (0.50) CYP3A4ALOX15POLBALDH1A1PPARG
SCHEMBL11062497 0.76 ELANE (0.38) CYP3A4ALOX15ALDH1A1SMN1; SMN2TP53
SCHEMBL241385 0.74 ALOX15 (0.37) CYP3A4ALOX15ALDH1A1TSHRALOX12
SCHEMBL2001926 0.74 ALOX5 (0.46) CYP3A4ALOX15POLBALDH1A1TSHR
SCHEMBL9003874 0.74 KLF10 (0.37) CYP3A4ALOX15POLBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US claimed
US-9512333-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2016-12-06 US disclosed
EP-2417168-B1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS HUNTSMAN ADV MAT AMERICAS INC (US) 2014-11-26 EP disclosed
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
US-20130231021-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-09-05 US disclosed
US-8445699-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-05-21 US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 WO disclosed
EP-2417168-A1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS Huntsman Advanced Materials Americas LLC (US) 2012-02-15 EP disclosed
US-20120003892-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions Huntsman Advanced Materials Americans LLC (US) 2012-01-05 US disclosed
EP-0517656-A2 Fire-protected polyimide composition CIBA-GEIGY AG (CH) 1992-12-09 EP disclosed
US-5138000-A High strength molding material CIBA-GEIGY CORPORATION (US) 1992-08-11 US disclosed
EP-0457732-A1 Curable compositions CIBA-GEIGY AG (CH) 1991-11-21 EP disclosed
EP-0385937-A1 Curable blends based on aromatic bismaleinimides CIBA-GEIGY AG (CH) 1990-09-05 EP disclosed
EP-0348345-A2 Solution stable polyimide resin systems CIBA-GEIGY AG (CH) 1989-12-27 EP disclosed
EP-0227598-B1 STABLE COMPOSITIONS CONTAINING IMIDES CIBA-GEIGY AG (CH) 1989-08-02 EP disclosed
US-4749767-A IMPREGNATED YARN LAMINATE CIBA-GEIGY CORPORATION (US) 1988-06-07 US disclosed
EP-0235084-A2 Hot-curable compositions containing substituted bicyclo[2,2,1]hept-5-ene-2,3 imides of dicarboxylic acids and polymalein imide CIBA-GEIGY AG (CH) 1987-09-02 EP disclosed
US-4678849-A PREPREGS, COMPOSITES, COATINGS CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
EP-0227598-A1 Stable compositions containing imides CIBA-GEIGY AG (CH) 1987-07-01 EP disclosed