Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | FCER2 | P06734 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151530 | 0.88 | SYK (0.48) | SYKFCER2NTRK1NTRK3NTRK2 | |
| SCHEMBL24151507 | 0.84 | SYK (0.53) | SYKLMNAPOLBFCER2GAA | |
| SCHEMBL24152421 | 0.83 | LMNA (0.44) | SYKLMNAPOLBALDH1A1MAPK1 | |
| SCHEMBL24151529 | 0.83 | SYK (0.61) | SYKLMNAFCER2ALDH1A1NTRK1 | |
| SCHEMBL24151798 | 0.82 | SYK (0.44) | SYKPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL24152351 | 0.82 | NTRK1 (0.45) | SYKNTRK1NTRK3MEN1KMT2A | |
| SCHEMBL24152849 | 0.81 | MGAT2 (0.49) | SYKLMNAPOLBFCER2ALDH1A1 | |
| SCHEMBL24152477 | 0.80 | SYK (0.49) | SYKLMNAPOLBALDH1A1MEN1 | |
| SCHEMBL24152858 | 0.79 | NTRK1 (0.46) | SYKNTRK1MEN1KMT2ATLK2 | |
| SCHEMBL24151508 | 0.78 | IDO1 (0.47) | SYKALDH1A1CYP1A2CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |