Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL2417282

[Na+].[Na+].[SH-].[SH-]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrogen Sulfide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL6248 1.00
Hydrogen Sulfide SCHEMBL27402396 1.00 CA1 (1.00)
Lithium Ion SCHEMBL10456379 0.82
Water SCHEMBL2569159 0.82 CA1 (0.67)
Water SCHEMBL408583 0.82
Water SCHEMBL6690800 0.82
Hydrogen Sulfide SCHEMBL7407144 0.82
Hydrogen Sulfide SCHEMBL9239676 0.82
Water SCHEMBL2166809 0.82
Water SCHEMBL159554 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5427700-A Functional fluid with triglycerides, detergent-inhibitor additives and viscosity modifying additives THE LUBRIZOL CORPORATION (US) 1995-06-27 US claimed
US-5413725-A For internal combustion engines, triglycerides THE LUBRIZOL CORPORATION (US) 1995-05-09 US claimed
US-5338471-A Pour point depressants for industrial lubricants containing mixtures of fatty acid esters and vegetable oils THE LUBRIZOL CORPORATION (US) 1994-08-16 US claimed
US-5298177-A Power transmission fluids, overbased compounds, metal passivator, diarylamine, amine salt of carboxy containing copolymer THE LUBRIZOL CORPORATION (US) 1994-03-29 US claimed
EP-0554421-A1 FUNCTIONAL FLUID WITH TRIGLYCERIDES, DETERGENT-INHIBITOR ADDITIVES AND VISCOSITY MODIFYING ADDITIVES THE LUBRIZOL CORPORATION (US) 1993-08-11 EP claimed
WO-1993003123-A1 FUNCTIONAL FLUID WITH TRIGLYCERIDES, DETERGENT-INHIBITOR ADDITIVES AND VISCOSITY MODIFYING ADDITIVES THE LUBRIZOL CORPORATION (US) 1993-02-18 WO claimed
CN-118022990-A Copper sulfide mineral hydrophilizing agent and preparation and application methods thereof 长春黄金研究院有限公司 2024-05-14 CN disclosed
CN-115181042-B Method for preparing di (alkoxythiocarbonyl) thioether compound and preparing cyanuric acid compound simultaneously and application thereof 中南大学 2024-05-14 CN disclosed
CN-118043502-A Composition for copper electrodeposition comprising a polyaminoamide leveling agent 巴斯夫欧洲公司 2024-05-14 CN disclosed
CN-118002321-A Delafossite mineral flotation inhibitor and preparation method thereof 长春黄金研究院有限公司 2024-05-10 CN disclosed
CN-117960392-A Application of combined inhibitor in copper-molybdenum bulk concentrate flotation separation 中南大学 2024-05-03 CN disclosed
CN-115260496-B Process for producing polyarylene sulfide resin, and product and use thereof 浙江新和成特种材料有限公司 2024-03-29 CN disclosed
CN-117643969-A Preparation and application methods of double-target copper-molybdenum separation inhibitor 长春黄金研究院有限公司 2024-03-05 CN disclosed
CN-112063833-A Method for removing arsenic and inhibiting sulfur loss of copper concentrate 向双清 2020-12-11 CN disclosed
CN-108950200-B Method for recovering associated gold by dearsenifying gold-loaded high-arsenic copper concentrate 紫金矿业集团股份有限公司 2020-02-14 CN disclosed
EP-2374793-A1 METHOD FOR PRODUCING ALKENYL MERCAPTAN Sumitomo Chemical Company, Limited (JP) 2011-10-12 EP disclosed
US-20110218363-A1 METHOD FOR PRODUCING ALKENYL MERCAPTAN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-08 US disclosed
CN-1658910-A Polyurethane foam products with controlled release of agents and additives HH BROWN SHOE TECH INC (US) 2005-08-24 CN disclosed
EP-1052326-A1 Use of oxidized white liquor in a kraft mill digester AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-11-15 EP disclosed
US-4960841-A REACTING A PREPOLYMER WITH A MIXTURE OF A DIHALODIPHENYL-SULFONE OR A HALOGENATED AROMATIC COMPOUND AND A SULFIDIZATION AGENT IN A POLAR SOLVENT DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-10-02 US disclosed