Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241812 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1TOP2ASMN1; SMN2LMNA | |
| SCHEMBL13197267 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1TOP2ASMN1; SMN2LMNA | |
| SCHEMBL16471838 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1TOP2ASMN1; SMN2LMNA | |
| SCHEMBL21836280 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1TOP2ASMN1; SMN2LMNA | |
| SCHEMBL21836279 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1TOP2ASMN1; SMN2LMNA | |
| SCHEMBL15858692 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1TOP2ASMN1; SMN2LMNA | |
| SCHEMBL1256130 | 0.79 | KDM4E (0.73) | KDM4EALDH1A1TOP2ASMN1; SMN2LMNA | |
| SCHEMBL23180113 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1TOP2ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL7173470 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2LMNARAB9A | |
| Hydrochloric Acid SCHEMBL7177809 | 0.78 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363923-B1 | RHODIUM AND IRIDIUM COMPLEXES | MERCK PATENT GMBH (DE) | 2009-04-01 | — | — | EP | claimed |
| US-20240260448-A1 | Metal Complexes | UDC IRELAND LIMITED (IE) | 2024-08-01 | — | — | US | disclosed |
| US-11917901-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11005050-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| US-10290819-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2019-05-14 | — | — | US | disclosed |
| US-9859504-B2 | Diamine compounds for phosphorescent diazaborole metal complexes and electroluminescent devices | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-01-02 | — | — | US | disclosed |
| US-9853228-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-26 | — | — | US | disclosed |
| US-9837622-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-9831446-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-9768397-B2 | Phenylenediamine compounds for phosphorescent diazaborole metal complexes | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2017-09-19 | — | — | US | disclosed |
| US-8722898-B2 | — | — | 2014-05-13 | — | — | US | disclosed |
| US-8658832-B2 | Luminescent metal complexes for organic electronic devices | MERCK PATENT GMBH (DE) | 2014-02-25 | — | — | US | disclosed |
| US-20140045810-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| US-20130284977-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| US-20130253617-A1 | PHOSPHORUS-CONTAINING METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| WO-2013097920-A1 | METAL COMPLEXES COMPRISING 1,2,3-TRIAZOLES | MERCK PATENT GMBH (DE) | 2013-07-04 | — | — | WO | disclosed |
| US-20130116755-A1 | METAL COMPLEXES WITH ORGANIC LIGANDS AND USE THEREOF IN OLEDS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130082209-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-04-04 | — | — | US | disclosed |
| US-20120004407-A1 | METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME | MERCK PATENT GMBH (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20100176386-A1 | LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100176386-A1 | LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES | OCIAD2, OCIAD1, OSTC | KDM4E 4222/4885ALDH1A1 1304/4885TOP2A 4393/4885 |
| US-20120004407-A1 | METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME | ICOSLG, ERAL1, CTCF | KDM4E 2177/4885ALDH1A1 1796/4885TOP2A 4608/4885 |
| US-11005050-B2 | Metal complexes | SOD1, AP1M1, AP3M1 | KDM4E 3816/4885ALDH1A1 3721/4885TOP2A 3772/4885 |
| US-20130082209-A1 | METAL COMPLEXES | MCOLN2, MCOLN1, AP1M1 | KDM4E 4129/4885ALDH1A1 2790/4885TOP2A 3466/4885 |
| US-10290819-B2 | Metal complexes | PICALM, IMMT, IKZF3 | KDM4E 4377/4885ALDH1A1 2645/4885TOP2A 3189/4885 |
| US-11917901-B2 | Metal complexes | MCOLN2, MCOLN1, AP1M1 | KDM4E 4260/4885ALDH1A1 1631/4885TOP2A 3261/4885 |
| US-20240260448-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | KDM4E 3816/4885ALDH1A1 3721/4885TOP2A 3772/4885 |
| US-20140045810-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | KDM4E 3816/4885ALDH1A1 3721/4885TOP2A 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.