SCHEMBL241812

SCHEMBL241812

CC(=NC(C)C)c1ccccn1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.63
▸ ALDH1A1 P00352 3/20 0.52
▸ TOP2A P11388 2/20 0.49
▸ SMN1; SMN2 Q16637 5/20 0.48
▸ LMNA P02545 4/20 0.48
▸ MITF O75030 1/20 0.48
▸ RAB9A P51151 4/20 0.46
▸ MAPT P10636 3/20 0.46
▸ MEN1 O00255 2/20 0.46
▸ GAA P10253 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ ALOX12 P18054 1/20 0.46
▸ GFER P55789 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ SLC2A1 P11166 1/20 0.46
▸ CES2 O00748 1/20 0.45
▸ CES1 P23141 1/20 0.45
▸ NPC1 O15118 4/20 0.44
▸ L3MBTL1 Q9Y468 3/20 0.44
▸ HTT P42858 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241811 1.00 KDM4E (0.63) KDM4EALDH1A1TOP2ASMN1; SMN2LMNA
SCHEMBL13197267 0.82 KDM4E (0.56) KDM4EALDH1A1TOP2ASMN1; SMN2LMNA
SCHEMBL16471838 0.82 KDM4E (0.56) KDM4EALDH1A1TOP2ASMN1; SMN2LMNA
SCHEMBL21836280 0.80 KDM4E (0.58) KDM4EALDH1A1TOP2ASMN1; SMN2LMNA
SCHEMBL21836279 0.80 KDM4E (0.58) KDM4EALDH1A1TOP2ASMN1; SMN2LMNA
SCHEMBL15858692 0.80 KDM4E (0.53) KDM4EALDH1A1TOP2ASMN1; SMN2LMNA
SCHEMBL1256130 0.79 KDM4E (0.73) KDM4EALDH1A1TOP2ASMN1; SMN2LMNA
SCHEMBL23180113 0.79 KDM4E (0.47) KDM4EALDH1A1TOP2ASMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL7173470 0.78 KDM4E (0.37) KDM4EALDH1A1SMN1; SMN2LMNARAB9A
Hydrochloric Acid SCHEMBL7177809 0.78 KDM4E (0.37) KDM4EALDH1A1SMN1; SMN2LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363923-B1 RHODIUM AND IRIDIUM COMPLEXES MERCK PATENT GMBH (DE) 2009-04-01 — — EP claimed
US-12635401-B2 Metal complexes UDC Ireland (IE) 2026-05-19 — — US disclosed
US-20260070936-A1 METAL COMPLEXES UDC IRELAND LTD (IE) 2026-03-12 — — US disclosed
EP-4069709-B1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-04-23 — — EP disclosed
US-12250871-B2 Metal complexes UDC IRELAND LIMITED (IE) 2025-03-11 — — US disclosed
US-20240260448-A1 Metal Complexes UDC IRELAND LIMITED (IE) 2024-08-01 — — US disclosed
US-11917901-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 — — US disclosed
US-20230056324-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-02-23 — — US disclosed
EP-4069709-A1 METAL COMPLEXES Merck Patent GmbH (DE) 2022-10-12 — — EP disclosed
US-11404649-B2 Electroluminescent bridged metal complexes for use in electronic devices MERCK PATENT GMBH (DE) 2022-08-02 — — US disclosed
US-20120004407-A1 METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME MERCK PATENT GMBH (DE) 2012-01-05 — — US disclosed
US-20110284799-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2011-11-24 — — US disclosed
EP-2297275-B1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-11-23 — — EP disclosed
US-20110144366-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-06-16 — — US disclosed
US-20110108769-A1 Complexes for Use In Optoelectronic Components MERCK PATENT GMBH (DE) 2011-05-12 — — US disclosed
US-20110089410-A1 Electronic Device Comprising Metal Complexes MERCK PATENT GMBH (DE) 2011-04-21 — — US disclosed
US-7816531-B2 Metal complexes MERCK PATENT GMBH (DE) 2010-10-19 — — US disclosed
US-20100176386-A1 LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2010-07-15 — — US disclosed
US-20080027220-A1 Metal Complexes MERCK PATENT GMBH (DE) 2008-01-31 — — US disclosed
CN-1829725-A aromatic monomer and conjugated polymer-metal complex SUMITOMO CHEMICAL CO (JP) 2006-09-06 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070936-A1 METAL COMPLEXES SCO2, CBR1, CORO1C KDM4E 4498/4885ALDH1A1 2087/4885TOP2A 3872/4885
US-12635401-B2 Metal complexes SCO2, SOD1, NR4A1 KDM4E 3445/4885ALDH1A1 2069/4885TOP2A 2604/4885
US-20100176386-A1 LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES OCIAD2, OCIAD1, OSTC KDM4E 4222/4885ALDH1A1 1304/4885TOP2A 4393/4885
US-12250871-B2 Metal complexes AP1M1, SOD1, AP3M1 KDM4E 3628/4885ALDH1A1 3790/4885TOP2A 4088/4885
US-20230056324-A1 METAL COMPLEXES MCU, IMMT, SOD1 KDM4E 4474/4885ALDH1A1 1713/4885TOP2A 2545/4885
US-20110284799-A1 METAL COMPLEXES SOD1, AP1M1, AP3M1 KDM4E 3816/4885ALDH1A1 3721/4885TOP2A 3772/4885
US-20120004407-A1 METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME ICOSLG, ERAL1, CTCF KDM4E 2177/4885ALDH1A1 1796/4885TOP2A 4608/4885
US-11404649-B2 Electroluminescent bridged metal complexes for use in electronic devices MCOLN2, MCOLN1, NCLN KDM4E 4201/4885ALDH1A1 1380/4885TOP2A 3174/4885
US-20080027220-A1 Metal Complexes AP1M1, SOD1, AP1G1 KDM4E 3323/4885ALDH1A1 363/4885TOP2A 3240/4885
US-20110108769-A1 Complexes for Use In Optoelectronic Components OSTC, INTS9, NBAS KDM4E 3731/4885ALDH1A1 3930/4885TOP2A 2275/4885
US-20110089410-A1 Electronic Device Comprising Metal Complexes AP1M1, EXOC1, SOD1 KDM4E 3484/4885ALDH1A1 900/4885TOP2A 3939/4885
US-11917901-B2 Metal complexes MCOLN2, MCOLN1, AP1M1 KDM4E 4260/4885ALDH1A1 1631/4885TOP2A 3261/4885
US-20110144366-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AP1M1, L1CAM, SOD1 KDM4E 3812/4885ALDH1A1 288/4885TOP2A 3913/4885
US-20240260448-A1 Metal Complexes SOD1, AP1M1, AP3M1 KDM4E 3816/4885ALDH1A1 3721/4885TOP2A 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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