Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | CASP7 | P55210 | 3/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980667 | 0.81 | CYP1A2 (0.40) | ALDH1A1CYP1A2MAOBMAOACYP3A4 | |
| SCHEMBL983515 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP1A2MAOBMAOACYP3A4 | |
| SCHEMBL24574648 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL979238 | 0.73 | TAS2R8 (0.32) | ALDH1A1CYP1A2MAOBMAOACYP3A4 | |
| SCHEMBL981042 | 0.73 | LRRK2 (0.34) | ALDH1A1LRRK2CYP1A2MAOBMAOA | |
| SCHEMBL15339557 | 0.72 | CYP1A2 (0.38) | ALDH1A1LRRK2CYP1A2MAOBMAOA | |
| SCHEMBL1198707 | 0.71 | LMNA (0.49) | ALDH1A1CYP1A2HSD17B10CYP2C9MEN1 | |
| SCHEMBL22363263 | 0.71 | LRRK2 (0.41) | ALDH1A1LRRK2CYP1A2MAOBMAOA | |
| SCHEMBL24184530 | 0.70 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP3A4HSD17B10MAPK1 | |
| Hydrochloric Acid SCHEMBL31078258 | 0.69 | IDO1 (0.43) | ALDH1A1CYP1A2MAOBMAOACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348426-A1 | OXOPYRROLIDINE FPR2 AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230348426-A1 | OXOPYRROLIDINE FPR2 AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-11-02 | — | — | US | disclosed |
| CN-116034104-A | Oxo-pyrrolidine FPR2 agonists | 百时美施贵宝公司 | 2023-04-28 | — | — | CN | disclosed |
| WO-2022011084-A1 | OXOPYRROLIDINE FPR2 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348426-A1 | OXOPYRROLIDINE FPR2 AGONISTS | FPR1, FPR2, FPR3 | ALDH1A1 3918/4885LRRK2 2562/4885CYP1A2 1040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.