Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MITF | O75030 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15705515 | 0.80 | MEN1 (0.39) | ALDH1A1HSD17B10CYP1A2CYP3A4USP2 | |
| SCHEMBL22363263 | 0.75 | LRRK2 (0.41) | ALDH1A1HSD17B10CYP1A2CYP3A4USP2 | |
| SCHEMBL15703047 | 0.73 | MEN1 (0.39) | ALDH1A1HSD17B10CYP1A2CYP3A4USP2 | |
| SCHEMBL26692301 | 0.73 | MEN1 (0.39) | ALDH1A1SMN1; SMN2HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL978628 | 0.72 | HTT (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2MITF | |
| SCHEMBL25755264 | 0.72 | NPC1 (0.36) | ALDH1A1RAB9ANPC1SMN1; SMN2MITF | |
| SCHEMBL25756148 | 0.72 | NPBWR1 (0.61) | ALDH1A1SMN1; SMN2PKMHTT | |
| SCHEMBL20786916 | 0.71 | NPC1 (0.55) | ALDH1A1RAB9ANPC1SMN1; SMN2MITF | |
| SCHEMBL24184142 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MAPTHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL15705517 | 0.70 | MEN1 (0.37) | ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348426-A1 | OXOPYRROLIDINE FPR2 AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230348426-A1 | OXOPYRROLIDINE FPR2 AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-11-02 | — | — | US | disclosed |
| CN-116034104-A | Oxo-pyrrolidine FPR2 agonists | 百时美施贵宝公司 | 2023-04-28 | — | — | CN | disclosed |
| WO-2022011084-A1 | OXOPYRROLIDINE FPR2 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348426-A1 | OXOPYRROLIDINE FPR2 AGONISTS | FPR1, FPR2, FPR3 | ALDH1A1 3918/4885RAB9A 4398/4885NPC1 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.