Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 7/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.42 |
| ▸ | HTR3B | O95264 | 4/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19012355 | 0.70 | HRH4 (0.46) | CYP1A2KDM4EALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL24190273 | 0.69 | XPO1 (0.33) | CYP1A2ALDH1A1CYP2C19CYP2D6 | |
| SCHEMBL856329 | 0.69 | PTK2 (0.47) | CYP1A2KDM4EALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL28758652 | 0.66 | CYP1A2 (0.41) | CYP1A2KDM4EALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL28758653 | 0.66 | CYP1A2 (0.41) | CYP1A2KDM4EALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL13135641 | 0.66 | HRH4 (0.59) | CYP1A2KDM4EALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL860986 | 0.65 | SMN1; SMN2 (0.45) | CYP1A2KDM4EALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL3238492 | 0.65 | SMN1; SMN2 (0.45) | CYP1A2KDM4EALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL17537344 | 0.65 | ADRB2 (0.48) | CYP1A2KDM4EALDH1A1CYP2C19CYP3A4 | |
| SCHEMBL25138077 | 0.65 | HTR3A (0.70) | CYP1A2KDM4EALDH1A1HTR3AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250063-A1 | PYRAZOLONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-10 | — | — | US | disclosed |
| WO-2022011083-A1 | PYRAZOLONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250063-A1 | PYRAZOLONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | FPR2, FPR1, FPR3 | CYP1A2 1716/4885KDM4E 4738/4885ALDH1A1 4372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.