Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196882 | 0.85 | HAO1 (0.39) | HRH3SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL24196020 | 0.72 | PRMT6 (0.35) | KCNH2 | |
| SCHEMBL24196886 | 0.71 | MAPT (0.35) | ALDH1A1LMNAMAPT | |
| SCHEMBL24196890 | 0.71 | PTPN1 (0.37) | HRH3SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL24196887 | 0.70 | CA2 (0.34) | SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL24196865 | 0.69 | SIGMAR1 (0.36) | LMNAMAPT | |
| SCHEMBL24196877 | 0.69 | ALDH1A1 (0.43) | HRH3ALDH1A1LMNAMAPT | |
| SCHEMBL12603832 | 0.68 | HRH3 (0.41) | KCNH2HRH3HTR1DDRD2SPHK1 | |
| SCHEMBL24196900 | 0.67 | HDAC1 (0.37) | HTR1DSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL24196866 | 0.66 | MEN1 (0.43) | SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |