Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196889 | 0.85 | KCNH2 (0.33) | LMNAALDH1A1MAPTSMN1; SMN2HRH3 | |
| SCHEMBL24196888 | 0.78 | ALDH1A1 (0.42) | LMNAALDH1A1MAPTRORCHTT | |
| SCHEMBL24196877 | 0.77 | ALDH1A1 (0.43) | LMNAALDH1A1MAPTRORCHTT | |
| SCHEMBL24196020 | 0.74 | PRMT6 (0.35) | CARM1PRMT6 | |
| SCHEMBL24196886 | 0.73 | MAPT (0.35) | LMNAALDH1A1MAPTCYP2C9HPGD | |
| SCHEMBL24196890 | 0.73 | PTPN1 (0.37) | ALDH1A1MAPTSMN1; SMN2HRH3CARM1 | |
| SCHEMBL11410136 | 0.73 | LMNA (0.44) | HAO1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27315791 | 0.72 | HRH3 (0.54) | HAO1LMNAALDH1A1NOS3NOS1 | |
| SCHEMBL24196887 | 0.72 | CA2 (0.34) | LMNAALDH1A1MAPTSMN1; SMN2TP53 | |
| SCHEMBL24196865 | 0.71 | SIGMAR1 (0.36) | LMNAMAPTTP53ATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |