Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | HTR7 | P34969 | 4/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32686717 | 0.84 | ADRA2A (0.41) | CYP2D6ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL10247785 | 0.84 | ADRA2A (0.41) | CYP2D6ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL24210469 | 0.80 | DRD2 (0.48) | HTR1AHTR7CHRM2CHRM1CHRM3 | |
| SCHEMBL16233586 | 0.77 | ADRA2A (0.49) | CYP2D6ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL20131349 | 0.77 | HTR7 (0.63) | HTR1AHTR7 | |
| SCHEMBL9183738 | 0.76 | DRD2 (0.58) | CYP2D6ADRA1AADRA1BHTR1AHTR7 | |
| SCHEMBL9759195 | 0.75 | DRD2 (0.52) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL6961243 | 0.75 | DRD2 (0.57) | CYP2D6ADRA1AADRA1BHTR1AHTR7 | |
| SCHEMBL599314 | 0.74 | CYP19A1 (0.54) | ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL8315435 | 0.74 | HTR1A (0.71) | CYP2D6ADRA1AADRA1BHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017541-A1 | INHIBITORS OF ARGINASE | Praxis Biotech LLC | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017541-A1 | INHIBITORS OF ARGINASE | ARG1, ARG2, ARGLU1 | CYP2D6 2935/4885ADRA2A 3155/4885ADRA2B 2342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.