SCHEMBL242176

SCHEMBL242176

FC(F)Oc1ccc(CBr)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.42
DRD1 P21728 1/20 0.42
LMNA P02545 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HTT P42858 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ATM Q13315 2/20 0.41
PKM P14618 2/20 0.41
HSP90AA1 P07900 1/20 0.41
HPGD P15428 1/20 0.41
CCR6 P51684 1/20 0.41
ALOX15 P16050 1/20 0.41
GFER P55789 1/20 0.41
ADAM17 P78536 1/20 0.41
MAPT P10636 2/20 0.41
ALOX12 P18054 1/20 0.41
POLB P06746 1/20 0.40
SLC6A4 P31645 1/20 0.40
ACACB O00763 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14486934 0.83 DAO (0.47) DAODRD1LMNAALDH1A1HTT
SCHEMBL6640503 0.83 TRPA1 (0.36) DAOALDH1A1POLBTRPA1TSHR
SCHEMBL11065049 0.80 DRD1 (0.56) DAODRD1LMNAALDH1A1HTT
SCHEMBL7767028 0.79 DAO (0.45) DAODRD1LMNAALDH1A1HTT
SCHEMBL29270714 0.79 TRPA1 (0.33) ALDH1A1POLBTRPA1TSHR
SCHEMBL21816578 0.78 RAB9A (0.43) DRD1MAPTMAPK1L3MBTL1NPC1
SCHEMBL31375546 0.78 RAB9A (0.40) DRD1MAPTMAPK1L3MBTL1NPC1
SCHEMBL3850797 0.77 IDO1 (0.52) DAODRD1LMNAALDH1A1HTT
SCHEMBL962797 0.77 DAO (0.42) DAODRD1LMNAALDH1A1HTT
SCHEMBL1780636 0.77 PPARG (0.51) DAODRD1LMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092052-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2026-04-02 US disclosed
US-20260078111-A1 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2026-03-19 US disclosed
EP-4692085-A2 PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS Nxera Pharma UK Limited (GB) 2026-02-11 EP disclosed
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) SHANGHAI DEGRON BIOMEDICAL TECH CO LTD (CN) 2026-02-05 US disclosed
EP-4041388-B1 PROSTAGLANDIN EP4 RECEPTOR ANTAGONIST COMPOUNDS NXERA PHARMA UK LTD (GB) 2025-11-26 EP disclosed
EP-4630401-A2 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF Rutgers, the State University of New Jersey (US) 2025-10-15 EP disclosed
EP-4626880-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) Shanghai Degron Biomedical Technology Co., Ltd. (CN) 2025-10-08 EP disclosed
US-20250288587-A1 Methods of Treating Fibrosis ATHIRA PHARMA, INC. (US) 2025-09-18 US disclosed
US-20250275975-A1 Methods of Treating Neuropathies ATHIRA PHARMA, INC. (US) 2025-09-04 US disclosed
US-20250275976-A1 Methods of Treating Neuroinflammatory Conditions ATHIRA PHARMA, INC. (US) 2025-09-04 US disclosed
WO-2001064639-A2 PDE IV INHIBITING AMIDES, COMPOSITIONS AND PHARMACEUTICAL USE MERCK FROSST CANADA & CO. (CA) 2001-09-07 WO disclosed
WO-2001062758-A1 PTERIDINE COMPOUNDS FOR THE TREATMENT OF PSORIASIS ASTRAZENECA AB (SE) 2001-08-30 WO disclosed
WO-2001028992-A2 NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS ASTRAZENECA AB (SE) 2001-04-26 WO disclosed
US-6048852-A BACTERICIDES SMITHKLINE BEECHAM P.L.C. (GB) 2000-04-11 US disclosed
EP-0900197-A1 BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS SMITHKLINE BEECHAM PLC (GB) 1999-03-10 EP disclosed
WO-1997030027-A1 BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS SMITHKLINE BEECHAM PLC (GB) 1997-08-21 WO disclosed
US-4405639-A INSECTICIDES; PESTICIDES; MITICIDES; NEMATOCIDES; PARACITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1983-09-20 US disclosed
US-4348323-A FLUORINE-CONTAINING BENZODIOXINE INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-09-07 US disclosed
US-4284643-A Combating arthropods with novel fluorine-containing phenylacetic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
EP-0008732-A2 Fluorine-containing esters of phenylacetic acids, process for their preparation and their use as insecticides and acaricides; intermediate products for their preparation BAYER AG (DE) 1980-03-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092052-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND CHRM1, CHRM2, CHRM4 DAO 1520/4885DRD1 194/4885LMNA 3673/4885
US-20250288587-A1 Methods of Treating Fibrosis HDGF, HGF, MMP1 DAO 3051/4885DRD1 4880/4885LMNA 1865/4885
US-20250275976-A1 Methods of Treating Neuroinflammatory Conditions HGF, HDGF, NGF DAO 2835/4885DRD1 4605/4885LMNA 2682/4885
US-20250275975-A1 Methods of Treating Neuropathies NGF, HGF, HDGF DAO 2471/4885DRD1 4801/4885LMNA 1644/4885
US-20260078111-A1 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF CA6, CA9, CA7 DAO 75/4885DRD1 3834/4885LMNA 1949/4885
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) ELAVL1, ELAVL3, HNRNPL DAO 3362/4885DRD1 3446/4885LMNA 1137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.