Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30081357 | 1.00 | MEN1 (0.44) | MEN1KMT2AIKBKBGAAALDH1A1 | |
| SCHEMBL16234345 | 0.83 | KDM4E (0.51) | MEN1KMT2AIKBKBALDH1A1HPGD | |
| SCHEMBL7660079 | 0.81 | MEN1 (0.42) | MEN1KMT2AIKBKBGAAALDH1A1 | |
| SCHEMBL28230815 | 0.79 | KMT2A (0.47) | MEN1KMT2AIKBKBGAAALDH1A1 | |
| SCHEMBL23632474 | 0.79 | MEN1 (0.44) | MEN1KMT2AIKBKBGAAALDH1A1 | |
| SCHEMBL5861172 | 0.79 | TSHR (0.54) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL2422281 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL28231761 | 0.76 | KMT2A (0.44) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL28231808 | 0.76 | MEN1 (0.41) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL28055302 | 0.75 | HTR3A (0.41) | MEN1KMT2AIKBKBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230125667-A1 | NOVEL TDZD ANALOGS AS AGENTS THAT DELAY, PREVENT, OR REVERSE AGE-ASSOCIATED DISEASES AND AS ANTI-CANCER AND ANTILEUKEMIC AGENTS | US GOV VETERANS AFFAIRS (US) | 2023-04-27 | — | — | US | disclosed |
| EP-2046733-B1 | PROCESS FOR THE PREPARATION OF EPSILON-ALKOXYCARBONYLLYSINES AND THEIR ANALOGUES | ITALIANA SINT SPA (IT) | 2011-10-05 | — | — | EP | disclosed |
| US-8026372-B2 | Process for the preparation of ε-alkoxycarbonyllysines and their analogues | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2011-09-27 | — | — | US | disclosed |
| US-20090312557-A1 | PROCESS FOR THE PREPARATION OF EPSILON -ALKOXYCARBONYLLYSINES AND THEIR ANALOGUES | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2009-12-17 | — | — | US | disclosed |
| EP-2046733-A1 | PROCESS FOR THE PREPARATION OF EPSILON-ALKOXYCARBONYLLYSINES AND THEIR ANALOGUES | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008014811-A1 | PROCESS FOR THE PREPARATION OF ε-ALKOXYCARBONYLLYSINES AND THEIR ANALOGUES | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2008-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312557-A1 | PROCESS FOR THE PREPARATION OF EPSILON -ALKOXYCARBONYLLYSINES AND THEIR ANALOGUES | AADAT, ALKBH3, BCAT2 | MEN1 4482/4885KMT2A 73/4885IKBKB 239/4885 |
| US-20230125667-A1 | NOVEL TDZD ANALOGS AS AGENTS THAT DELAY, PREVENT, OR REVERSE AGE-ASSOCIATED DISEASES AND AS ANTI-CANCER AND ANTILEUKEMIC AGENTS | BRCA1, MTPN, MUSK | MEN1 302/4885KMT2A 1067/4885IKBKB 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.