Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL14685915 | 0.97 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRMGAMGAA | |
| Propylene Glycol SCHEMBL5153420 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRMGAMGAA | |
| Propylene Glycol SCHEMBL20496489 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRMGAMGAA | |
| Propylene Glycol SCHEMBL472051 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRMGAMGAA | |
| Propylene Glycol SCHEMBL140963 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRMGAMGAA | |
| Propylene Glycol SCHEMBL186272 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRMGAMGAA | |
| Isobutanol SCHEMBL9078512 | 0.86 | ALDH1A1 (0.59) | ALDH1A1TDP1TSHRMGAMGAA | |
| Propylene Glycol SCHEMBL1274149 | 0.86 | TDP1 (0.59) | ALDH1A1TDP1TSHRMGAMGAA | |
| Propylene Glycol SCHEMBL3316533 | 0.86 | TDP1 (0.59) | ALDH1A1TDP1TSHRMGAMGAA | |
| Glycerin SCHEMBL6342405 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1939 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4155343-B1 | LATEX COMPOSITION | SUMITOMO SEIKA CHEMICALS (JP) | 2026-04-29 | — | — | EP | claimed |
| US-20260086456-A1 | METHOD OF MANUFACTURING ORGANOMETALLIC OXIDE CLUSTER, PHOTORESIST COMPOSITION INCLUDING THE ORGANOMETALLIC OXIDE CLUSTER, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE USING THE PHOTORESIST COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2026-03-26 | — | — | US | claimed |
| US-12577410-B2 | Rheology control agents for water-based resins and water-based paint compositions | KUSUMOTO CHEMICALS, LTD. (JP) | 2026-03-17 | — | — | US | claimed |
| EP-4217439-B1 | THERMALLY STABLE POLYTHIOL LIGANDS WITH PENDANT SOLUBILIZING MOIETIES | SHOEI CHEMICAL IND CO (JP) | 2026-02-18 | — | — | EP | claimed |
| US-12534639-B2 | Michael addition curable composition, coating composition containing the same, and coated article | Sherwin-Williams (Guangdong) New Material Co., Ltd. (CN) | 2026-01-27 | — | — | US | claimed |
| CN-120156034-A | Composite dispergation preparation for catalyzing resin degradation and preparation method and application thereof | 山东双圆生物科技有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-119615635-B | Corrosion-resistant polyurethane composite protective film for battery and preparation method thereof | 广州富思德新材料科技有限公司 | 2025-05-20 | — | — | CN | claimed |
| EP-4540306-A1 | MICHAEL ADDITION CURABLE COMPOSITION, ITS APPLICATION AND PROCESS FOR PREPARING MODIFIED EPOXY RESIN SUITABLE FOR THE SAME | Guangdong Huarun Paints Co., Ltd. (CN) | 2025-04-23 | — | — | EP | claimed |
| CN-119823639-A | UV (ultraviolet) curing coating and preparation method and application thereof | 浙江安益新材料有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119639295-A | High planarization film layer for TFT color filter and preparation method thereof | 四川蜀旺辰昇新材料有限责任公司 | 2025-03-18 | — | — | CN | claimed |
| EP-0663935-A4 | AQUEOUS NITROCELLULOSE COMPOSITIONS. | AGRIFILM INC (US) | 1996-04-17 | — | — | EP | claimed |
| EP-0663935-A1 | AQUEOUS NITROCELLULOSE COMPOSITIONS | AGRIFILM, INC. (US) | 1995-07-26 | — | — | EP | claimed |
| US-5308402-A | Furfuryl alcohol mixtures for use as cleaning agents | KYZEN CORPORATION (US) | 1994-05-03 | — | — | US | claimed |
| WO-1994007952-A1 | AQUEOUS NITROCELLULOSE COMPOSITIONS | AGRI-FILM, INC. (US) | 1994-04-14 | — | — | WO | claimed |
| US-5284885-A | Aqueous nitrocellulose compositions | AGRI-FILM, INC. (US) | 1994-02-08 | — | — | US | claimed |
| US-5268260-A | Free radical initiated addition polymerizable acrylate monomer | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1993-12-07 | — | — | US | claimed |
| US-5128057-A | Furfuryl alcohol mixtures for use as cleaning agents | KYZEN CORPORATION (US) | 1992-07-07 | — | — | US | claimed |
| EP-0436457-A2 | Photosensitive polyimide compositions | International Business Machines Corporation (US) | 1991-07-10 | — | — | EP | claimed |
| EP-0426512-A2 | Tetrahydrofurfuryl alcohol mixtures used as cleaning agents | KYZEN CORPORATION (US) | 1991-05-08 | — | — | EP | claimed |
| EP-0293084-A2 | Reaction products of reactive silicone, polyol, and isocyanate, urethane-siloxane copolymers and coating compositions, methods of coating, coated articles, and prepolymer solutions thereof | LORD CORPORATION (US) | 1988-11-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577410-B2 | Rheology control agents for water-based resins and water-based paint compositions | RER1, WDR82, CA1 | ALDH1A1 1237/4885TDP1 2827/4885TSHR 4636/4885 |
| US-12534639-B2 | Michael addition curable composition, coating composition containing the same, and coated article | PCNA, ILK, MGMT | ALDH1A1 313/4885TDP1 1411/4885TSHR 4868/4885 |
| US-20260086456-A1 | METHOD OF MANUFACTURING ORGANOMETALLIC OXIDE CLUSTER, PHOTORESIST COMPOSITION INCLUDING THE ORGANOMETALLIC OXIDE CLUSTER, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE USING THE PHOTORESIST COMPOSITION | TST, CSNK1A1L, CSNK1D | ALDH1A1 2964/4885TDP1 4608/4885TSHR 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.