SCHEMBL242519

SCHEMBL242519

CC(=Nc1c(C(C)C)cccc1C(C)C)c1ccccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
ALDH1A1 P00352 2/20 0.43
TOP2A P11388 2/20 0.42
NPC1 O15118 5/20 0.42
RAB9A P51151 5/20 0.42
AGTR1 P30556 5/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 2/20 0.42
MITF O75030 1/20 0.42
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
OPRK1 P41145 2/20 0.41
ALOX12 P18054 1/20 0.40
GFER P55789 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
SLC2A1 P11166 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL242518 1.00 KDM4E (0.53) KDM4EALDH1A1TOP2ANPC1RAB9A
SCHEMBL8166694 1.00 KDM4E (0.53) KDM4EALDH1A1TOP2ANPC1RAB9A
SCHEMBL8167553 0.98 KDM4E (0.51) KDM4EALDH1A1TOP2ANPC1RAB9A
Hydrochloric Acid SCHEMBL5083705 0.98 KDM4E (0.51) KDM4EALDH1A1TOP2ANPC1RAB9A
SCHEMBL16471834 0.91 KDM4E (0.47) KDM4EALDH1A1TOP2ANPC1RAB9A
SCHEMBL5589427 0.91 KDM4E (0.47) KDM4EALDH1A1TOP2ANPC1RAB9A
SCHEMBL5693530 0.90 KDM4E (0.46) KDM4EALDH1A1TOP2ANPC1RAB9A
SCHEMBL8172155 0.86 KDM4E (0.44) KDM4EALDH1A1NPC1RAB9AAGTR1
SCHEMBL20094447 0.86 KDM4E (0.54) KDM4EALDH1A1TOP2ANPC1RAB9A
Hydrochloric Acid SCHEMBL8173542 0.85 KDM4E (0.42) KDM4EALDH1A1NPC1RAB9AAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10981846-B1 Producing cyclic fuels from conjugated diene THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2021-04-20 US claimed
EP-1363923-B1 RHODIUM AND IRIDIUM COMPLEXES MERCK PATENT GMBH (DE) 2009-04-01 EP claimed
US-12635401-B2 Metal complexes UDC Ireland (IE) 2026-05-19 US disclosed
US-20260070936-A1 METAL COMPLEXES UDC IRELAND LTD (IE) 2026-03-12 US disclosed
EP-4069709-B1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-04-23 EP disclosed
US-12250871-B2 Metal complexes UDC IRELAND LIMITED (IE) 2025-03-11 US disclosed
CN-119504872-A Metal complex UDC爱尔兰有限公司 2025-02-25 CN disclosed
CN-113646317-B Metal complex UDC爱尔兰有限公司 2024-10-18 CN disclosed
CN-114787173-B Metal complex UDC爱尔兰有限公司 2024-10-18 CN disclosed
US-20240260448-A1 Metal Complexes UDC IRELAND LIMITED (IE) 2024-08-01 US disclosed
US-11917901-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-20110108769-A1 Complexes for Use In Optoelectronic Components MERCK PATENT GMBH (DE) 2011-05-12 US disclosed
US-20110101327-A1 Electronic Devices Comprising Metal Complexes Having Isonitrile Ligands MERCK PATENT GMBH (DE) 2011-05-05 US disclosed
US-20110089410-A1 Electronic Device Comprising Metal Complexes MERCK PATENT GMBH (DE) 2011-04-21 US disclosed
CN-101098899-B Polyethylene and catalyst composition for its preparation BASELL POLYOLEFINE GMBH 2011-04-13 CN disclosed
US-7816531-B2 Metal complexes MERCK PATENT GMBH (DE) 2010-10-19 US disclosed
CN-101824111-A Polyethylene and the catalyst composition that is used for its preparation BASELL POLYOLEFINE GMBH 2010-09-08 CN disclosed
US-20100176386-A1 LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2010-07-15 US disclosed
US-20080027220-A1 Metal Complexes MERCK PATENT GMBH (DE) 2008-01-31 US disclosed
CN-101098899-A Polyethylene and catalyst composition for its preparation BASELL POLYOLEFINE GMBH (DE) 2008-01-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070936-A1 METAL COMPLEXES SCO2, CBR1, CORO1C KDM4E 4498/4885ALDH1A1 2087/4885TOP2A 3872/4885
US-12635401-B2 Metal complexes SCO2, SOD1, NR4A1 KDM4E 3445/4885ALDH1A1 2069/4885TOP2A 2604/4885
US-20100176386-A1 LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES OCIAD2, OCIAD1, OSTC KDM4E 4222/4885ALDH1A1 1304/4885TOP2A 4393/4885
US-12250871-B2 Metal complexes AP1M1, SOD1, AP3M1 KDM4E 3628/4885ALDH1A1 3790/4885TOP2A 4088/4885
US-20110101327-A1 Electronic Devices Comprising Metal Complexes Having Isonitrile Ligands EXOC4, ICMT, NCLN KDM4E 3403/4885ALDH1A1 2323/4885TOP2A 4307/4885
US-10981846-B1 Producing cyclic fuels from conjugated diene FDFT1, PC, NDUFS8 KDM4E 2761/4885ALDH1A1 900/4885TOP2A 1970/4885
US-20080027220-A1 Metal Complexes AP1M1, SOD1, AP1G1 KDM4E 3323/4885ALDH1A1 363/4885TOP2A 3240/4885
US-20110108769-A1 Complexes for Use In Optoelectronic Components OSTC, INTS9, NBAS KDM4E 3731/4885ALDH1A1 3930/4885TOP2A 2275/4885
US-20110089410-A1 Electronic Device Comprising Metal Complexes AP1M1, EXOC1, SOD1 KDM4E 3484/4885ALDH1A1 900/4885TOP2A 3939/4885
US-11917901-B2 Metal complexes MCOLN2, MCOLN1, AP1M1 KDM4E 4260/4885ALDH1A1 1631/4885TOP2A 3261/4885
US-20240260448-A1 Metal Complexes SOD1, AP1M1, AP3M1 KDM4E 3816/4885ALDH1A1 3721/4885TOP2A 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.