Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252373 | 0.82 | HDAC4 (0.33) | PRMT5WDR77HDAC4 | |
| SCHEMBL24252217 | 0.78 | — | — | |
| SCHEMBL24252375 | 0.78 | CYP2C8 (0.31) | — | |
| SCHEMBL24252212 | 0.75 | CTDSP1 (0.33) | PRMT5WDR77 | |
| SCHEMBL24252374 | 0.75 | ROCK2 (0.32) | PRMT5WDR77 | |
| SCHEMBL24252370 | 0.74 | ROCK2 (0.34) | PRMT5WDR77 | |
| SCHEMBL24252229 | 0.73 | LRRK2 (0.35) | — | |
| SCHEMBL24252410 | 0.70 | CCNT1 (0.33) | — | |
| SCHEMBL24252214 | 0.69 | — | — | |
| SCHEMBL1456807 | 0.66 | GOT1 (0.46) | PRMT5WDR77HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |