Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252215 | 0.82 | PRMT5 (0.32) | HDAC4PRMT5WDR77 | |
| SCHEMBL24252217 | 0.77 | — | — | |
| SCHEMBL24252375 | 0.77 | CYP2C8 (0.31) | EGLN1 | |
| SCHEMBL24252212 | 0.74 | CTDSP1 (0.33) | ALDH1A1MAPK1PRMT5WDR77 | |
| SCHEMBL24252374 | 0.74 | ROCK2 (0.32) | PRMT5WDR77 | |
| SCHEMBL24252370 | 0.73 | ROCK2 (0.34) | PRMT5WDR77 | |
| SCHEMBL24252229 | 0.72 | LRRK2 (0.35) | — | |
| SCHEMBL24252409 | 0.71 | CCNT1 (0.33) | P2RX7 | |
| SCHEMBL24252372 | 0.70 | ALDH1A1 (0.33) | ALDH1A1TP53MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL1456807 | 0.65 | GOT1 (0.46) | HDAC4ALDH1A1TP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113630-A | Process for preparing pyridazinone derivatives | 先正达农作物保护股份公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |