SCHEMBL24254091

SCHEMBL24254091

c1ccc(-c2cccc(-c3c4ccccc4c(-c4ccc5c6c(cccc46)-c4ccccc4Sc4ccccc4-5)c4ccccc34)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
PTGER1 P34995 1/20 0.33
PTGER4 P35408 1/20 0.33
PTGER3 P43115 1/20 0.33
PTGER2 P43116 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.32
APAF1 O14727 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22969354 0.96 PTGER1 (0.32) PTGER1PTGER4PTGER3PTGER2L3MBTL1
SCHEMBL22969178 0.94 PTGER1 (0.31) PTGER1PTGER4PTGER3PTGER2L3MBTL1
SCHEMBL24254090 0.91 CRHBP (0.37) CRHBPCRHR2KEAP1NFE2L2L3MBTL1
SCHEMBL22969342 0.87 ACHE (0.33) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL22969353 0.87 ACHE (0.35) CRHBPCRHR2KEAP1NFE2L2MAPT
SCHEMBL22969362 0.86 ACHE (0.33) CRHBPCRHR2KEAP1NFE2L2PTGER1
SCHEMBL22969193 0.86 ACHE (0.33) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL22969186 0.85 ACHE (0.34) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL16558476 0.85 THRB (0.33) L3MBTL1MEN1APAF1NPC1LMNA
SCHEMBL22969187 0.84 ACHE (0.32) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220052272-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220052272-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TMEM109, OR10J3, LEF1 CRHBP 4859/4885CRHR2 4827/4885KEAP1 1125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.