Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316240 | 0.79 | CYP1B1 (0.41) | KDM4E | |
| SCHEMBL24315752 | 0.79 | HDAC8 (0.40) | KDM4E | |
| SCHEMBL24315912 | 0.77 | KDM4E (0.34) | KDM4E | |
| SCHEMBL24316089 | 0.74 | MAPT (0.41) | — | |
| SCHEMBL24315846 | 0.71 | LMNA (0.39) | — | |
| SCHEMBL24317766 | 0.70 | MAPT (0.34) | KDM4E | |
| SCHEMBL23267574 | 0.70 | MAPT (0.35) | — | |
| SCHEMBL24317938 | 0.69 | ALDH1A1 (0.39) | KDM4E | |
| SCHEMBL24317937 | 0.67 | KMT2A (0.41) | — | |
| SCHEMBL22550089 | 0.66 | KMT2A (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081925-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |