Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316240 | 0.78 | CYP1B1 (0.41) | MAPTL3MBTL1ALDH1A1MEN1HTT | |
| SCHEMBL24315752 | 0.75 | HDAC8 (0.40) | L3MBTL1HTR1ALMNA | |
| SCHEMBL24315912 | 0.74 | KDM4E (0.34) | MAPTALDH1A1HTTKMT2ALMNA | |
| SCHEMBL24315949 | 0.74 | KDM4E (0.32) | — | |
| SCHEMBL24315846 | 0.72 | LMNA (0.39) | MAPTDRD2MEN1KMT2AHTR1A | |
| SCHEMBL24317938 | 0.72 | ALDH1A1 (0.39) | MAPTNPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL24316313 | 0.72 | UBE2M (0.39) | ALDH1A1DRD4MEN1KMT2ALMNA | |
| SCHEMBL24317937 | 0.71 | KMT2A (0.41) | MAPTL3MBTL1TDP1ALDH1A1MEN1 | |
| SCHEMBL7121196 | 0.69 | L3MBTL1 (0.54) | MAPTL3MBTL1NPSR1TDP1ALDH1A1 | |
| SCHEMBL7121956 | 0.69 | MEN1 (0.48) | MAPTL3MBTL1NPSR1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081925-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |