Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316545 | 0.89 | CSF1R (0.43) | CSF1RPIK3CAMTORALKBH1KDM4E | |
| SCHEMBL24316434 | 0.87 | CSF1R (0.53) | CSF1RPIK3CAMTORALKBH1KDM4E | |
| SCHEMBL24316565 | 0.86 | CSF1R (0.44) | CSF1RPIK3CAMTORALKBH1KDM4E | |
| SCHEMBL24316658 | 0.82 | CSF1R (0.42) | CSF1RALKBH1KDM4EALDH1A1GRM5 | |
| SCHEMBL24316982 | 0.82 | CSF1R (0.48) | CSF1RPIK3CAMTORALKBH1KDM4E | |
| SCHEMBL24316659 | 0.81 | ALKBH1 (0.40) | CSF1RALKBH1KDM4EALDH1A1GRM5 | |
| SCHEMBL24316554 | 0.81 | CSF1R (0.42) | CSF1RPIK3CAMTOR | |
| SCHEMBL24316814 | 0.81 | CSF1R (0.47) | CSF1RPIK3CAMTORKDM4EALDH1A1 | |
| SCHEMBL24316428 | 0.81 | ALKBH1 (0.39) | CSF1RALKBH1KDM4EALDH1A1GRM5 | |
| SCHEMBL24316983 | 0.80 | CSF1R (0.46) | CSF1RPIK3CAMTORALKBH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |